메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Mahvash Zargar (Department of Obstetrics and Gynecology; Fertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences) Mehri Ghafourian (Department of Immunology, Fertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences) Farnaz Behrahi (Department of Obstetrics and Gynecology; Fertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences) Roshan Nikbakht (Department of Obstetrics and Gynecology; Fertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences) Abdolah Mousavi Salehi (Department of Immunology, Fertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences)
저널정보
대한산부인과학회 Obstetrics & Gynecology Science Obstetrics & Gynecology Science Vol.67 No.1
발행연도
2024.1
수록면
112 - 119 (8page)
DOI
10.5468/ogs.23120

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Objective Fetal uterine survival depends on maintaining an immune balance between the mother and fetus. This study aimed to investigate the correlation of blood peripheral natural killer (NK) cells and interferon-gamma (IFN-γ) with recurrent recurrent implantation failure (RIF) and recurrent pregnancy loss (RPL). Methods In this case-control study, peripheral blood samples were obtained from three groups of RPL, RIF, and parous women without a history of abortion or infertility problems and analyzed by lymphocyte-based flow cytometry. Afterward, the levels of NK cells and IFN-γ were determined. All data were analyzed using one-way analysis of variance and nonparametric Kruskal-Wallis tests. Results The level of IFN-γ in the RPL group was significantly higher than that in parous women and the RIF group (P<0.05), whereas its level in the RIF group was not significantly different from the control group (P>0.05). A significant correlation was found between the levels of IFN-γ and NK cells in the RPL group (r=0.481; P=0.02). However, no significant correlation was found between the levels of IFN-γ and the active NK cells in the RPL group (P=0.08). Moreover, no significant correlation was found between the levels of NK cells (whether activated or not) and IFN-γ in the RIF patients (P>0.05). Conclusion Immune dysfunction may not be involved in implantation failure during IVF but may be involved in recurrent miscarriage, probably by increasing IFN-γ levels.

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

최근 본 자료

전체보기

댓글(0)

0