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자료유형
학술저널
저자정보
Hongryeol Park (Max-Planck Institute for Molecular Biomedicine) Chan Hee Lee (Hallym University)
저널정보
대한면역학회 Immune Network Immune Network Vol.24 No.3
발행연도
2024.6
수록면
51 - 71 (21page)

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초록· 키워드

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The brain and lungs, vital organs in the body, play essential roles in maintaining overall wellbeing and survival. These organs interact through complex and sophisticated bi-directional pathways known as the ’lung–brain axis’, facilitated by their close proximity and neural connections. Numerous studies have underscored the mediation of the lung-brain axis by inflammatory responses and hypoxia-induced damage, which are pivotal to the progression of both pulmonary and neurological diseases. This review aims to delve into how pulmonary diseases, including acute/chronic airway diseases and pulmonary conditions, can instigate neurological disorders such as stroke, Alzheimer’s disease, and Parkinson’s disease. Additionally, we highlight the emerging research on the lung microbiome which, drawing parallels between the gut and lungs in terms of microbiome contents, may play a significant role in modulating brain health. Ultimately, this review paves the way for exciting avenues of future research and therapeutics in addressing respiratory and neurological diseases.

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ABSTRACT
INTRODUCTION
ASSOCIATION OF BRAIN DISEASES WITH LUNG DISEASES
DISCUSSION
REFERENCES

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