지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.6
- 수록면
- 1 - 9 (9page)
- DOI
- 10.1038/s12276-024-01266-3
이용수
초록· 키워드
오류제보하기
MicroRNAs (miRNAs) are pivotal regulators of gene expression and are involved in biological processes spanning from early developmental stages to the intricate process of aging. Extensive research has underscored the fundamental role of miRNAs in orchestrating eukaryotic development, with disruptions in miRNA biogenesis resulting in early lethality. Moreover, perturbations in miRNA function have been implicated in the aging process, particularly in model organisms such as nematodes and flies. miRNAs tend to be clustered in vertebrate genomes, finely modulating an array of biological pathways through clustering within a single transcript. Although extensive research of their developmental roles has been conducted, the potential implications of miRNA clusters in regulating aging remain largely unclear. In this review, we use the Mir-23-27-24 cluster as a paradigm, shedding light on the nuanced physiological functions of miRNA clusters during embryonic development and exploring their potential involvement in the aging process. Moreover, we advocate further research into the intricate interplay among miRNA clusters, particularly the Mir-23-27-24 cluster, in shaping the regulatory landscape of aging.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
타겟 유전자 기반 miRNA 네트워크를 통한 질병 관련 miRNA 추출 방법
한국정보기술학회논문지
2015 .01
-
miRNA Pattern Discovery from Sequence Alignment
JIPS(Journal of Information Processing Systems)
2017 .01
-
Utilizing microRNAs for self-modulating RNA therapy
한국생물공학회 학술대회
2021 .10
-
Rules for functional microRNA targeting
BMB Reports
2017 .01
-
딥러닝을 활용한 오토인코더 기반 질병 관련 miRNA 예측 연구
한국정보기술학회논문지
2022 .06
-
MicroRNA–Gene Association Prediction Method using Deep Learning Models
Journal of information and communication convergence engineering
2023 .12
-
Structural Characterization of pre-miRNA 155
Journal of the Korean Magnetic Resonance Society
2016 .01
-
Identification of pre-miRNA using convolutional neural network
대한전자공학회 학술대회
2020 .08
-
Post-transcriptional and translational regulation of mRNA-like long non-coding RNAs by microRNAs in early developmental stages of zebrafish embryos
BMB Reports
2017 .01
-
Non-canonical targets play an important role in microRNA stability control mechanisms
BMB Reports
2017 .01
-
DNA–Gold Nanoparticle Conjugates for Intracellular miRNA Detection Using Surface-Enhanced Raman Spectroscopy
BioChip Journal
2022 .03
-
딥러닝 기반 miRNA-mRNA 연관성 예측 모델 연구
대한전자공학회 학술대회
2024 .06
-
Developing miRNA-Inducible Vector System for Tissue-Specific Cargo Expression
한국생물공학회 학술대회
2024 .09
-
Efficient generation of human induced pluripotent stem cells using self-assembled siRNA/miRNA nanoparticles
한국생물공학회 학술대회
2018 .10
-
Highly Sensitive Exosomal miRNA Detection System Based on Successive Toehold-Mediated DNA Strand Displacement within Fusogenic Vesicles
한국고분자학회 학술대회 연구논문 초록집
2021 .10
-
miRNA-Gene association prediction method by Autoencoder and LSTM Deep Learning Model
INTERNATIONAL CONFERENCE ON FUTURE INFORMATION & COMMUNICATION ENGINEERING
2023 .01
-
A Microfluidic Device-based Assay for Dual Target miRNA
한국고분자학회 학술대회 연구논문 초록집
2023 .10
-
The expression and functional roles of microRNAs in stem cell differentiation
BMB Reports
2016 .01
-
RNA-binding proteins and exoribonucleases modulating miRNA in cancer: the enemy within
Experimental and Molecular Medicine
2024 .05
최근 본 자료
댓글(0)
0