지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Psoriasis is a chronic inflammatory skin disease that occurs worldwide. Clinically, it is characterized by well-defined erythematous plaques with thick silvery scales occurring anywhere on the body. Treatment for psoriasis is broadly divided into two categories: topical therapy and systemic therapy. While numerous effective systemic therapies, including biologics, are available for moderate to severe psoriasis patients, topical therapy still holds an important position in psoriasis management.
This is because approximately 70~90% of psoriasis patients have mild to moderate disease, which can often be managed with topical therapies alone. Various topical agents are currently utilized for psoriasis treatment. Representative examples include topical corticosteroids, calcineurin inhibitors, vitamin D analogues, moisturizers, and salicylic acid. They target different aspects of psoriasis pathogenesis, including inflammation and abnormal keratinocyte proliferation. These topical agents are a key component of psoriasis treatment. However, overall satisfaction with topical therapy may be limited. Previous studies cite several reasons for this, including dissatisfaction with side effects, excessive treatment regimen complexity, inadequate cosmetic acceptance, and low effectiveness. In this review, we aim to explore the current topical agents for psoriasis treatment, as well as discuss their limitations and strategies for overcoming them.
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