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논문 기본 정보

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학술저널
저자정보
Joongmin Kim (Severance Cardiovascular Hospital) Young-Guk Ko (Severance Cardiovascular Hospital) Seung-Jun Lee (Severance Cardiovascular Hospital) Chul-Min Ahn (Severance Cardiovascular Hospital) Seung-Woon Rha (Korea University Guro Hospital) Cheol Ung Choi (Korea University Guro Hospital) Pil-Ki Min (Gangnam Severance Hospital) Jong Kwan Park (National Health Insurance Service Ilsan Hospital) Ji-Yong Jang (National Health Insurance Service Ilsan Hospital) Young Jin Youn (Yonsei University Wonju College of Medicine) Tae-Soo Kang (Dankook University College of Medicine) Chang-Hwan Yoon (Seoul National University Bundang Hospital) Donghoon Choi (Severance Cardiovascular Hospital)
저널정보
대한심장학회 Korean Circulation Journal Korean Circulation Journal Vol.54 No.9
발행연도
2024.9
수록면
565 - 576 (12page)
DOI
https://doi.org/10.4070/kcj.2024.0038

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Background and Objectives: The K-ELUVIA study aimed to investigate the clinical effectiveness and safety of Eluvia™, a polymer-coated, paclitaxel-eluting stent, for femoropopliteal artery disease using data from a prospective Korean multicenter registry. Methods: A total of 105 patients with femoropopliteal artery disease who received endovascular treatment (EVT) with Eluvia™ stents at 7 Korean sites were enrolled in a prospective cohort and followed for 2 years. The primary endpoint was the 2-year clinical patency. The secondary endpoint was 2-year freedom from clinically driven target lesion revascularization (TLR). Results: Mean patient age was 68.2±10.4 years, and most patients (82.7%) were male. Mean lesion length was 168.3±117.6 mm. Chronic total occlusion was found in 57.7% of patients. Trans-Atlantic Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II) type C or D lesions were present in 46.1% of patients. Procedural success was achieved in 99.0% of patients. The clinical patency rate was 84.4% at 1 year after EVT and 76.3% at 2 years post-EVT. The freedom from TLR rate was 89.1% at 1 year after EVT and 79.1% at 2 years post-EVT. Chronic total occlusion (hazard ratio [HR], 3.53; 95% confidence interval [CI], 1.08–11.67; p=0.039) and smaller mean stent diameter (HR, 0.40; 95% CI, 0.16–0.98; p=0.044) were identified as independent predictors of loss of clinical patency at 2 years. Conclusions: The K-ELUVIA study demonstrated favorable 2-year clinical effectiveness and safety outcomes of Eluvia stent for femoropopliteal artery lesions in real-world practice.

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