지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.8
- 수록면
- 363 - 374 (12page)
- DOI
- 10.3393/ac.2024.00521.0074
이용수
초록· 키워드
오류제보하기
Metastatic lateral pelvic lymph nodes (LPNs) in rectal cancer significantly impact the prognosis and treatment strategies. Western practices emphasize neoadjuvant chemoradiotherapy (CRT), whereas Eastern approaches often rely on LPN dissection (LPND). This review examines the evolving role of LPND in the context of modern treatments, including total neoadjuvant therapy (TNT), and the impact of CRT on the management of clinically suspicious LPNs. We comprehensively reviewed the key literature comparing the outcomes of LPND versus preoperative CRT for rectal cancer, focusing on recent advancements and ongoing debates. Key studies, including the JCOG0212 trial and recent multicenter trials, were analyzed to assess the efficacy of LPND, particularly in conjunction with preoperative CRT or TNT. Current evidence indicates that LPND can reduce local recurrence rates compared to total mesorectal excision alone in patients not receiving radiation therapy. However, the benefit of LPND in the context of neoadjuvant CRT is influenced by the size and pretreatment characteristics of LPNs. While CRT can effectively control smaller metastatic LPNs, larger or clinically suspicious LPNs may require LPND for optimal outcomes. Advances in surgical techniques, such as robotic-assisted LPND, offer potential benefits but also present challenges and complications. The role of TNT in controlling metastatic LPNs and improving patient outcomes is emerging but remains underexplored. The decision to perform LPND should be individualized based on patient-specific factors, including LPN size, response to neoadjuvant treatment, and surgeon expertise. Future research should focus on optimizing treatment protocols and further evaluating the role of TNT in managing metastatic LPNs.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Standardized Step-by-step Technique Using Surgical Landmarks in Robotic Lateral Pelvic Lymph Node Dissection
Annals of Coloproctology
2021 .01
-
Early Systemic Failure After Preoperative Chemoradiotherapy for the Treatment of Patients With Rectal Cancer
Annals of Coloproctology
2019 .01
-
Difference in Tumor Area as a Predictor of a Pathological Complete Response for Patients With Locally Advanced Rectal Cancer
Annals of Coloproctology
2017 .01
-
Neoadjuvant Therapy to Optimize Patients" Outcome: Localized advanced rectal cancer: chemoradiation vs. TNT
대한임상종양학회 학술대회지
2021 .06
-
Matched case-control analysis comparing oncologic outcomes between preoperative and postoperative chemoradiotherapy for rectal cancer
Annals of Surgical Treatment and Research
2017 .04
-
Radiofrequency ablation using real-time ultrasonography?computed tomography fusion imaging improves treatment outcomes for T1a renal cell carcinoma: Comparison with laparoscopic partial nephrectomy
Investigative and Clinical Urology
2022 .03
-
Clinical influence of neoadjuvant chemoradiotherapy on immunonutritional status in locally advanced rectal cancer
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2023 .06
-
Recent Update of Total Neoadjuvant Therapy for Rectal Cancer
대한외과학회 학술대회 초록집
2022 .05
-
ERRATUM: Difference in prognostic impact of lateral pelvic lymph node metastasis between pre- and post-neoadjuvant chemoradiotherapy in rectal cancer patients
Annals of Surgical Treatment and Research
2024 .09
-
New Perspectives on Predictive Biomarkers of Tumor Response and Their Clinical Application in Preoperative Chemoradiation Therapy for Rectal Cancer
Yonsei Medical Journal
2015 .01
-
Effect of lateral lymph node dissection on the quality of life and genitourinary function after neoadjuvant chemoradiotherapy for rectal cancer
Annals of Surgical Treatment and Research
2021 .02
-
Treatment Outcomes of Neoadjuvant Chemoradiation Therapy for Rectal Cancer Patients: A Nationwide Population-based Cohort Study in Korea
대한외과학회 학술대회 초록집
2020 .11
-
Impact of circumferential tumor location of mid to low rectal cancer on oncologic outcomes after preoperative chemoradiotherapy
Annals of Surgical Treatment and Research
2022 .08
-
Effect of leukocyte alteration on treatment outcomes following preoperative chemoradiotherapy in patients with rectal cancer
Radiation oncology journal : ROJ
2017 .01
-
Prediction of Pathologic Response to Neoadjuvant Chemoradiotherapy in Patients with Esophageal Squamous Cell Carcinoma Incorporating Hematological Biomarkers
Cancer Research and Treatment
2021 .01
-
Comparison of Chemoradiation Therapy vs. Adjuvant Chemotherapy Alone in Patients with Extremely Low Rectal Cancer Requiring Abdominoperineal Resection
대한외과학회 학술대회 초록집
2021 .05
-
Lateral Pelvic Node Dissection for Locally Advanced Rectal Cancer in Korea
대한외과학회 학술대회 초록집
2019 .10
-
Local Recurrence after Neoadjuvant Chemoradiotherapy And Rectal Excision in Rectal Cancer Patients When The Distal Resection Margin Is Compromised
대한외과학회 학술대회 초록집
2020 .11
-
Predictive factors of prolonged warm ischemic time (≥30 minutes) during partial nephrectomy under pneumoperitoneum
Investigative and Clinical Urology
2015 .01
-
Modifications to Treatment Plan of Rectal Cancer in Response to COVID-19 at the Philippine General Hospital
Annals of Coloproctology
2021 .08
최근 본 자료
댓글(0)
0