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논문 기본 정보

자료유형
학술저널
저자정보
문익준 (울산대학교 의과대학 서울아산병원 피부과) 이우진 (울산대학교 서울아산병원 피부과) 고현창 (부산대학교) 김효진 (인제대학교 의과대학 부산백병원 피부과) 나찬호 (조선대학교 의과대학 피부과학교실) 박준수 (대구가톨릭대학교) 박진 (전북대학교) 서현민 (한양대학교) 신민경 (경희대학교) 이영복 (가톨릭대학교) 장용현 (경북대학교) 정혜정 (국립중앙의료원) 이양원 (건국대학교)
저널정보
대한의진균학회 대한의진균학회지 Journal of Mycology and Infection Vol.29 No.3
발행연도
2024.9
수록면
117 - 136 (20page)

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초록· 키워드

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Background: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause various cutaneous complications, including dermatologic adverse reactions to SARS-CoV-2 vaccines reported by several studies. Objective: To describe the clinical characteristics of cutaneous complications of SARS-CoV-2 infection and adverse reactions to SARS-CoV-2 vaccines, and to determine the risk factors for cutaneous manifestations. Methods: A questionnaire-based survey in 12 hospitals in Korea. Results: After receiving SARS-CoV-2 vaccinations, 20.23% and 5.94% of the respondents reported new-onset cutaneous lesions or aggravation of preexisting cutaneous conditions, respectively. Respondents who developed new cutaneous lesions after COVID-19 were significantly older than those who did not (p = 0.001). Systemic symptoms of SARS-CoV-2 vaccination (fever, chill, cough, sore throat, and myalgia) were associated with higher risk for new-onset cutaneous lesions (p < 0.05). Myalgia was the only systemic symptom of SARS-CoV-2 vaccination that was associated with higher risk for the aggravation of preexisting cutaneous conditions (p = 0.011). Following coronavirus 2019 (COVID-19) diagnosis, 13.3% and 9.7% of the respondents reported new skin lesions and aggravation of preexisting cutaneous conditions, respectively. Respondents with new cutaneous lesions were significantly older than those without new cutaneous lesions (p = 0.046). Systemic COVID-19 symptoms were significantly more common in respondents who developed new cutaneous lesions than in those who did not (p < 0.001). The proportion of respondents with underlying autoimmune diseases was significantly higher in those with cutaneous COVID-19 complications than in those without such complications (p = 0.038). Conclusion: This study offers insights into the characteristics of cutaneous manifestations of SARS-CoV-2 vaccination and infection in Korea.

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