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논문 기본 정보

자료유형
학술저널
저자정보
Hadis Amini Tameh (Shahid Beheshti University) Saeed Imani (Shahid Beheshti University) Jaber Alizadehgoradel (University of Zanjan) Alireza Noroozi (Tehran University of Medical Sciences)
저널정보
대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience Vol.22 No.3
발행연도
2024.8
수록면
512 - 519 (8page)
DOI
10.9758/cpn.24.1163

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초록· 키워드

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Objective: This study aimed to analyze the effect of the intensified transcranial direct-current stimulation (tDCS) targeting bilateral dorsolateral prefrontal cortex (DLPFC) on craving reduction in patients with opioid use disorder. Methods: This quasi-experimental study was conducted on 30 individuals who participated voluntarily at Baharan Camp of Shahid Mahalati. The participants had already completed the detoxification phase and stayed at the camp to resolve their craving and gain occupational skills to reintegrate into the community. The participants were selected using con venience and purposive sampling methods and were then assigned to an experimental group (n = 15) and a control group (n = 15). The experimental group received ten 20-minute tDCS sessions twice a day for 5 consecutive days. There was a 20-minute break between the two stimulations. The DLPFC was stimulated with a current intensity of 2 mA (anode: F3 and cathode: F4). The control group received a sham stimulation. Both groups completed Franken’s Desires for Drug Questionnaire at baseline and after the stimulation sessions. Additionally, they completed the ques tionnaires once again three months after the end of the treatment to assess treatment retention. Results: At the posttest stage, the intensified tDCS had significant effects on momentary opioid craving reduction in all measured factors, e.g., desire and intention, negative reinforcement, and control (p < 0.001). However, the results concerning treatment retention at the 3-month follow-up stage were insignificant for all factors (p < 0.001). Conclusion: Apparently, tDCS can be used as a tool to reduce craving. However, its application as an independent and sustainable treatment remains debatable.

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