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Antioxidative and Antihypertensive Effects of Lycii fructus Extracts
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구기자(Lycii fructus) 추출물의 항산화와 항고혈압 효과

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Antioxidative and Antihypertensive Effects of Lycii fructus Extracts
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The physiological activity of Lycii fructus extracts were examined. Total phenolic contents in the ethanol extracts (9.5 ㎎/g) of Lycii fructus were higher than that of water extracts (8.7 ㎎/g). The chlorogenic acid (1.7 ㎍ in water extracts and 1.3 ㎍ in 60% ethanol extract) was the most abundant phenolic compound as analyzed by HPLC. The ABTS [2,2'-azinobis(3-ethylbenzothiaznoline-6-sulfornic acid)] radical decolorization electron donating ability (DPPH) and antioxidant protection factor (PF) were determined for extracts from Lycii fructus. Water extract (76.7% on ABTS, 92.6% on DPPH and 1.1 on PF) showed higher inhibition rate than 60% ethanol extracts (52.8%, 88.8% and 1.0). Thiobarbituric acid reactive substance (TBARS) was determined as 1.5×10-³ μM in 60% ethanol extract. Ethanol extracts was more effective in decreasing TBARS than water extracts. The water extracts from Lycii fructus had higher angiotensin converting enzyme (ACE) inhibition activity than ethanol extracts. The result will be useful for functional foods application and understanding the physiological activities of Lycii fructus.

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UCI(KEPA) : I410-ECN-0101-2009-511-018240385