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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.9
- 수록면
- 229 - 235 (7page)
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초록· 키워드
오류제보하기
Opuntia humifusa is a member of the Cactaceae family. In the present study, the antioxidant, nitric oxide (NO) inhibitory activities and potential irritation response of the fermented Opuntia humifusa cladodes (FOH) were investigated for cosmetic use. Antioxidant activities were tested using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and xanthine oxidase assay, we found that FOH could scavenge DPPH free radicals and inhibit xanthine oxidase activity in a dose dependent manner, with IC50 of 2599.46 ㎍/㎖ and 721.38 ㎍/㎖, respectively. To investigate the possible antiinflammatory effects of FOH, RAW 264.7 macrophages were pretreated with FOH (0~400 ㎍/㎖) for 30 min and then treated with LPS for 24 h. We found that cell number did not vary significantly with the treatment of FOH, and FOH did not show any inhibitory effects on LPS-induced NO production. After application of FOH to rabbits for skin and eye irritation test, the experimental sites did not show any response compared to the control. FOH were considered to be a non-irritant to the skin and eye. Based on the above information, we suggest that FOH can be considered to be a non-irritant base cosmetic material for safely use.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEGMENTS
REFERENCES
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UCI(KEPA) : I410-ECN-0101-2009-513-017426674