지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
To det ermine 8 anti-impotence drug/drug-like compounds such as sildenafil, vardenafil, tadalafil, homosildenafil, hydroxyhomosildenafil, aminotadalafil, pseudovardenafil and hongdenafil in foods, simultaneously, high performance liquid chromatograrhy(HPLC) and liquid chromatograthy-mass spectrometry (LC/MS) were used.
The HPLC/UV analysis was performed on a column of capcellpak C₁? with 0,1 % sodium-1-hexansulfonate in 0.2M ammonium formate/acetonitrile as a mobile phase. Mass spectra of the compounds by LC/MS were investigated with SCAN mode(Mass range and Fragment voltage) and SIM (Selected Ion Monitoring) mode (Ion target and Fragment voltage).
The results follow as;
1. The HPLC/UV analysis was detected from 5 out of 63 samples.
The content of sildenafil was in the range of 32.80 ppm~60,13 ppm from 4 out of 5 samples, The contents of sildenafil, vardenafil, homosildenafil were in the range 47,14 ppm from lout of 5 samples.
2. The conformed result of LC/MS was equal of detected from 5 out of 63 samples in HPLC/UV analysis.
An easily available, simultaneous determination of 8 standards in adulterated health related foods was established by using a combination of LC/MS methods.
The HPLC/UV analysis was performed on a column of capcellpak C₁? with 0,1 % sodium-1-hexansulfonate in 0.2M ammonium formate/acetonitrile as a mobile phase. Mass spectra of the compounds by LC/MS were investigated with SCAN mode(Mass range and Fragment voltage) and SIM (Selected Ion Monitoring) mode (Ion target and Fragment voltage).
The results follow as;
1. The HPLC/UV analysis was detected from 5 out of 63 samples.
The content of sildenafil was in the range of 32.80 ppm~60,13 ppm from 4 out of 5 samples, The contents of sildenafil, vardenafil, homosildenafil were in the range 47,14 ppm from lout of 5 samples.
2. The conformed result of LC/MS was equal of detected from 5 out of 63 samples in HPLC/UV analysis.
An easily available, simultaneous determination of 8 standards in adulterated health related foods was established by using a combination of LC/MS methods.
목차
Abstract
Ⅰ. 서론
Ⅱ. 재료 및 방법
Ⅲ. 결과 및 고찰
Ⅳ. 결론
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