지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.12
- 수록면
- 83 - 91 (9page)
이용수
초록· 키워드
오류제보하기
β-glucan is a fiber-type complex sugar (polysaccharide) derived from the cell wall of baker's yeast, oat and barley fiber, and many medicinal mushrooms, such as maitake. The primary uses of β-glucan are to enhance the immune system, to lower blood cholesterol levels and to treat tumor. β-glucan has no systemic toxicity in mice, therefore it needed clinical trail to prove efficacy and safety for human. The subjects total 56 healty volunteers were divided into two groups including taken β-glucan tablet group and placebo group. Subjects were taken two tablets per oral for 4 weeks. They had agreed to take part in this experiment, and didn`t take any other clinical trail products.After 4 weeks blood of subjects were checked. The check list are TNF-α, INF-γ, IL-2, IL-4, total WBC, differential WBC, RBC, hemoglobin, platelet, MCV, MCH, MCHC, HCT, Na, K, Ca, Cl, AST, ALT, ALP, γ-GTP, total protein, triglyceride, total cholesterol, total bilirubin, albumin, uric acid, creatinine, BUN, pH, protein, glucose, ketone body, blood, bilirubin. We evaluated efficacy by cytokines that compare before and after taking. Collected data were analyzed as two sample t-test, chi-square test and ANOVA using SAS V.9.1.This study results are that in TNF-α of 1st efficacy measurement item, all of two groups figure were increased significantly compare to before figure. In IL4 of 2nd efficacy measurement item, experimental group figure were decreased significantly but placebo group figure were increased.
The conclusions show that based on the above results, β-glucan has favorable effect to enhance immune system, especially IL4 results showed that it has effect to improve the allergic immune system.
The conclusions show that based on the above results, β-glucan has favorable effect to enhance immune system, especially IL4 results showed that it has effect to improve the allergic immune system.
목차
Ⅰ. 서론
Ⅱ. 연구대상 및 방법
Ⅲ. 결과
Ⅳ. 고찰
Ⅴ. 결론
Ⅵ. 참고문헌
참고문헌 (25)
참고문헌 신청
1. [학술지(정기간행물)] - Jincheon Sik / 1998 / The effect of Salviae Radix on immunocytes and tumor cell lines / Korean J. oriental medical patholigy 12 : 125 ~
2. [학술지(정기간행물)] - Gyungmi Park / 1999 / A literatural study on immunity / Dongguk J. The Institute of Oriental Medicine 8 : 1 ~ 33
3. [학술지(정기간행물)] - Hoyert DL / 1999 / final data for 1997 / Natl Vital Stat Rep. 47 : 1 ~ 104
4. [학술지(정기간행물)] - Sungkee Jo / 2002 / Effects of Hyebaton, an extract from herb mixture containing sunflower, on immune activity and metabolism of glucose and lipid / food industry and nutrition 7 : 27 ~
5. [학술지(정기간행물)] - 류혜숙 / 2007 / 식물 혼합(고들빼기, 돌미나리, 메밀, 톳, 생강) 추출물이 마우스 면역 세포 활성에 미치는 영향 / 한국식품영양학회지 20 (1) : 74 ~ 78
2. [학술지(정기간행물)] - Gyungmi Park / 1999 / A literatural study on immunity / Dongguk J. The Institute of Oriental Medicine 8 : 1 ~ 33
3. [학술지(정기간행물)] - Hoyert DL / 1999 / final data for 1997 / Natl Vital Stat Rep. 47 : 1 ~ 104
4. [학술지(정기간행물)] - Sungkee Jo / 2002 / Effects of Hyebaton, an extract from herb mixture containing sunflower, on immune activity and metabolism of glucose and lipid / food industry and nutrition 7 : 27 ~
5. [학술지(정기간행물)] - 류혜숙 / 2007 / 식물 혼합(고들빼기, 돌미나리, 메밀, 톳, 생강) 추출물이 마우스 면역 세포 활성에 미치는 영향 / 한국식품영양학회지 20 (1) : 74 ~ 78
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실험적으로 동맥경화증을 유발시킨 랫드에서 ${\beta}$-Glucan의 동맥경화 방어기전에 대한 연구
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Gamma-irradiated β-glucan induces immunomodulation and anticancer activity through MAPK and NF-κB pathways
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2002 .01
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혈중지질에 대한 진피추출물의 유효성 평가를 위한 인체적용시험 : 무작위배정, 이중맹검
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조직 재생을 위한 Poly (D, L-lactide-co-glycolide) 표면에 (1→3)(1→6)-ßglucan 고정에 대한 세포 점착 및 성장 효과
의공학회지
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Effect of β-Glucan from Aureobasidium pullulans on Rat Rib Fracture Healing
Laboratory Animal Research
2008 .03
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Phagocytic Effects of β-Glucans from the Mushroom Coriolus versicolor are Related to Dectin-1, NOS, TNF-α Signaling in Macrophages
Biomolecules & Therapeutics(구 응용약물학회지)
2011 .01
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