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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.2
- 수록면
- 156 - 160 (5page)
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This study was conducted to evaluate the hypotensive properties of the extract of Chinese balloon flower (Platycodon grandiflorum)’s root. In the studies for calcium channel-blocking using Xenopus oocytes, the ethanol-extract (26.2±5.2%) showed higher activity than water-extract. Twenty female rats were fed 25, 35, and 45 mg/kg BW/day of the ethanol-extract for 14 days to observe the changes in blood pressures and heart pulses. Ethanol-extract decreased the systolic, diastolic, and mean blood pressures of the rats. Especially, the rats fed with 45 mg/kg BW/day of the ethanol-extract showed significant decreases in the blood pressures. These results suggested that a decrease in blood pressures was due to the extension of a blood vessel with calcium channel-blocking by ethanol-extract of Chinese balloon flower. Forty %-ethanol showed the highest efficiency for ethanol-extraction of Chinese balloon flower.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Acknowledgments
References
참고문헌 (34)
참고문헌 신청
Bers DM , 1991 , Excitation-Contraction Coupling and Cardiac Contractile Force , Kluwer Academic : 26 ~ 27
Katz AM , 1992 , Physiology of Heart. 2nd ed , Raven Press : 35 ~ 38
Bolton RB , 1979 , Mechanism of action or transmitters and other substances on smooth muscle , Physiol. Rev 59 : 606 ~ 718
Godfraind T , 1979 , Alternative mechanism for the potentiation of the relaxation evoked by isoprenaline in aortae from young and aged rats , Eur. J. Pharmacol 53 : 273 ~ 279
Furchgott RF , 1976 , Sprial-cut strip of rabbit aorta for in vitro studies of response of arterial smooth muscle , Method Med. Res 8 : 177 ~ 186
Katz AM , 1992 , Physiology of Heart. 2nd ed , Raven Press : 35 ~ 38
Bolton RB , 1979 , Mechanism of action or transmitters and other substances on smooth muscle , Physiol. Rev 59 : 606 ~ 718
Godfraind T , 1979 , Alternative mechanism for the potentiation of the relaxation evoked by isoprenaline in aortae from young and aged rats , Eur. J. Pharmacol 53 : 273 ~ 279
Furchgott RF , 1976 , Sprial-cut strip of rabbit aorta for in vitro studies of response of arterial smooth muscle , Method Med. Res 8 : 177 ~ 186
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UCI(KEPA) : I410-ECN-0101-2013-573-001010103