지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.1
- 수록면
- 46 - 50 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: There is concern about the potential adverse effects on hepatic function due to increased intraabdominal pressure during pneumoperitoneum. The changes in hepatic function following a laparoscopy assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) for gastric cancer were compared.
Methods: Between July 2004 and May 2005, 60 patients diagnosed with early gastric cancer at Kangnam St’ Mary’s hospital; 30 each having undergone LADG and ODG were studied. The levels of alkaline phosphatase (ALP), total bilirubin (TB), aspartate transferase (AST) and alanine transferase (ALT) between the two groups were compared at 24 and 72 hours postoperatively.
Results: The age, sex, body mass index and preoperative hepatic function were not different between the two groups. The operative times were significantly longer in the LADG than the ODG group (298 vs. 184 minutes, P＜0.000). There was no postoperative hepatic failure or mortality in either group. The levels of ALP decreased, but those of total bilirubin remained unchanged from the preoperative baselines in both groups, with no significant difference between the two groups. After a LADG, the levels of AST and ALT increased 3.7 and 3.5 fold 24 hours after surgery, whereas after an ODG, the levels of AST and ALT increased 1.9 and 1.5 fold. In the LADG group, the levels of AST and ALT were significantly increased compared to the ODG group (P＜0.05), but returned close to the baseline levels within 72 hours. On the third postoperative day, there were no significant differences in the levels of AST and ALT between the two groups (P＞0.05).
Conclusion: After a LADG, the levels of hepatic transaminases were immediately elevated, but returned to normal levels within 72 hours. A LADG with prolonged pneumoperitoneum is considered safe in patients with normal liver function prior to the operation. In addition, to evaluate the safety of a LADG in the patients with decreased hepatic function, a large scaled randomized prospective trial will be required.
Methods: Between July 2004 and May 2005, 60 patients diagnosed with early gastric cancer at Kangnam St’ Mary’s hospital; 30 each having undergone LADG and ODG were studied. The levels of alkaline phosphatase (ALP), total bilirubin (TB), aspartate transferase (AST) and alanine transferase (ALT) between the two groups were compared at 24 and 72 hours postoperatively.
Results: The age, sex, body mass index and preoperative hepatic function were not different between the two groups. The operative times were significantly longer in the LADG than the ODG group (298 vs. 184 minutes, P＜0.000). There was no postoperative hepatic failure or mortality in either group. The levels of ALP decreased, but those of total bilirubin remained unchanged from the preoperative baselines in both groups, with no significant difference between the two groups. After a LADG, the levels of AST and ALT increased 3.7 and 3.5 fold 24 hours after surgery, whereas after an ODG, the levels of AST and ALT increased 1.9 and 1.5 fold. In the LADG group, the levels of AST and ALT were significantly increased compared to the ODG group (P＜0.05), but returned close to the baseline levels within 72 hours. On the third postoperative day, there were no significant differences in the levels of AST and ALT between the two groups (P＞0.05).
Conclusion: After a LADG, the levels of hepatic transaminases were immediately elevated, but returned to normal levels within 72 hours. A LADG with prolonged pneumoperitoneum is considered safe in patients with normal liver function prior to the operation. In addition, to evaluate the safety of a LADG in the patients with decreased hepatic function, a large scaled randomized prospective trial will be required.
목차
서론
방법
결과
고찰
결론
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Comparative Study of Laparoscopy-Assisted versus Open Subtotal Gastrectomy for pT2 Gastric Cancer
Yonsei Medical Journal
2012 .01
-
조기위암 치료에 대한 복강경보조 위절제술과 개복 위절제술에 있어서 비만도의 영향
Annals of Surgical Treatment and Research
2008 .08
-
복강경 보조 원위부 위절제술의 초기 경험
Annals of Surgical Treatment and Research
2008 .12
-
복강경 위절제술과 개복 위절제술을 유사한 시기에 수술자로서 경험한 외과 전문의의 수술 결과 및 생존율
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2011 .06
-
조기 위암의 복강경 보조 위절제술과 개복 위절제술의 비교
Annals of Surgical Treatment and Research
2007 .03
-
Preservation of Aberrant Left Hepatic Artery during LADG
대한외과학회 학술대회 초록집
2005 .05
-
복강경 보조하 근치적 위암 수술의 수술 중 합병증 분석
Annals of Surgical Treatment and Research
2007 .03
-
First experiences with laparoscopic assisted distal gastrectomy : in the view of comparison with high volume centers
Annals of Surgical Treatment and Research
2012 .09
-
Double stapling Roux-en-Y reconstruction in laparoscopy assisted distal gastrectomy(LADG)
대한외과학회 학술대회 초록집
2009 .11
-
Intraoperative Complications of LADG for Gastric cancer
대한외과학회 학술대회 초록집
2006 .05
-
Is there risk factors LADG itself? A retrospective study of 1000 cases at single high volume center
대한외과학회 학술대회 초록집
2009 .11
-
Comparison of short-term outcomes and acute inflammatory response between laparoscopy-assisted and totally laparoscopic distal gastrectomy for early gastric cancer
Annals of Surgical Treatment and Research
2015 .09
-
Comprehension of readmission after laparoscopy assisted distal gastrectomy : what are the causes?
Annals of Surgical Treatment and Research
2014 .05
-
Lessons Learned from a Comparative Analysis of Surgical Outcomes of and Learning Curves for Laparoscopy-Assisted Distal Gastrectomy
Journal of Gastric Cancer
2015 .01
-
The Learning Curve of LADG with Systemic Lymphadenectomy of Early Gastric Cancer
대한외과학회 학술대회 초록집
2005 .05
-
The case report of early gastric cancer with situs inversus patient performed LADG
대한외과학회 학술대회 초록집
2009 .11
-
High rates of complications in advanced stage gastric cancer after laparoscopic gastrectomy
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2017 .12
-
Comparison between LADG and RSG at stomach cancer surgery
대한외과학회 학술대회 초록집
2010 .11
-
Oncologic Outcomes after Laparoscopic and Open Distal Gastrectomy for Advanced Gastric Cancer: Propensity Score Matching Analysis
Journal of Gastric Cancer
2019 .01
-
조기 위암에서 수술시간을 고려한 복강경 보조하 위아전절제술의 학습곡선
Annals of Surgical Treatment and Research
2006 .02
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2013-514-002674657