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Stability of Purified Bee Venom on the Treatment Temperature
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온도에 따른 봉독의 성분 및 생리활성 변화

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Type
Academic journal
Author
Sangmi Han (농촌진흥청) Miran Cho (농촌진흥청) Myeonglyeol Lee (농촌진흥청) Manyoung Lee (농촌진흥청) Inpyo Hong (농촌진흥청) Soonok Woo (농촌진흥청) Jungmin Kim (농촌진흥청) Kwankyu Park (대구가톨릭대학교)
Journal
The Apicultural Society of Korea Journal of Apiculture Vol.28 No.3 KCI Accredited Journals
Published
2013.7
Pages
223 - 228 (6page)

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Stability of Purified Bee Venom on the Treatment Temperature
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Abstract· Keywords

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For the investigation of the stability of purified bee venom (PBV) during the treatment in the temperature range of 50°C to 120°C for 24 hours, respectively, melittin contents, antibacterial effects, and cell regenerations were investigated. The changes in the melittin contents of PBV were not significantly different by treatment temperature below 70°C for 24 houes and 80°C for 4 hours. However the melttin contents is great decline after 24 hours above 80°C for 24 hours. Antibacterial effects is not change below 80°C for 4 houes but significantly decrease above 80°C for 24 hours. Cell regenerations of PBV on human dermal fibroblast decreased at 80°C for 24 houes, showing a significant difference from the below 80°C for 4 houes. Through the temperature stability of PBV results of this study, it was treated that the melittin contents, antibacterial effects and cell regeneration effects of PBV could be maintained above 80°C for 4 hours.

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