지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.8
- 수록면
- 89 - 97 (9page)
이용수
초록· 키워드
오류제보하기
Backgrounds/Aims: Intrahepatic recurrence is one of the most important causes of compromised prognosis after surgical resection of hepatocellular carcinoma (HCC). This retrospective study was designed to identify and compare the risks of recurrence, early recurrence and multiple recurrences in a single patient population. Methods: A series of 92 consecutive patients, who received resection for single nodular HCC at our institute from January 2007 to December 2013, were enrolled in this study. The patients were divided into recurrent and non-recurrent groups; the recurrent group was further divided into subgroups by applying two criteria: early and late recurrence (with a cutoff of 18 months), and single and multiple (≥2) recurrence. The potential risk factors were compared using univariate and multivariate analyses. The subgroup analysis was performed to determine the effects of different cut-off values on the analysis. Results: 41 recurrences (44.6%) occurred during a mean follow-up of 42.4 months. The Child-Pugh score, and the portal vein invasion were found to be independent risk factors of recurrence, but differentiation was the only independent risk factor of early recurrence. The serum alpha-fetoprotein, tumor size, tumor necrosis, and hemorrhage were found to be the risk factors of multiple recurrences according to the univariate analysis, but lacked significance according to the multivariate analysis. When the cutoffs for early and multiple recurrences were changed to ≤10 months and ＞3 nodules, respectively, different risk factors were identified. Conclusions: Our results implicated that different factors can predict the recurrence, timing, and multiplicity of an HCC recurrence. Further studies should be conducted to prove the complex relationships between tumor burden, invasiveness, and underlying liver cirrhosis for initial tumors, and the timing and multiplicity of recurrent HCC.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Validation for models for tumor recurrence after liver transplantation in hepatectomy patients
Annals of Surgical Treatment and Research
2022 .03
-
Substantial risk of recurrence even after 5 recurrence-free years in early-stage hepatocellular carcinoma patients
Clinical and Molecular Hepatology
2020 .01
-
Change in the Recurrence Pattern and Predictors over Time after Complete Cure of Hepatocellular Carcinoma
Gut and Liver
2021 .01
-
Differences in Prognostic Factors between Early and Late Recurrence Breast Cancers
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Risk factors for poor survival after recurrence of hepatocellular carcinoma after liver transplantation
Annals of Surgical Treatment and Research
2021 .07
-
Protrusion of hepatocellular carcinoma is a predictor of early recurrence in hepatectomy patients after spontaneous rupture
Annals of Surgical Treatment and Research
2016 .06
-
Risk Factors and Tumor Recurrence in pT1N0M0 Gastric Cancer after Surgical Treatment
Journal of Gastric Cancer
2016 .01
-
Clinical significance and predictive factors of early massive recurrence after radiofrequency ablation in patients with a single small hepatocellular carcinoma
Clinical and Molecular Hepatology
2016 .01
-
Incidence and risk factors of recurrence of overactive bladder symptoms after discontinuation of successful medical treatment
Investigative and Clinical Urology
2017 .01
-
Prognosis of Hepatocellular Carcinoma after Liver Transplantation: Comparative Analysis with Partial Hepatectomy
Journal of Pathology and Translational Medicine
2017 .01
-
Early disseminated recurrence after liver resection in solitary hepatocellular carcinoma
Annals of Surgical Treatment and Research
2018 .03
-
Outcomes of Living Donor Liver Transplantation in Patients with a History of Ruptured Hepatocellular Carcinoma
대한외과학회 학술대회 초록집
2021 .05
-
Recurrent Spinal Giant Cell Tumors: A Study of Risk Factors and Recurrence Patterns
Asian Spine Journal
2016 .01
-
Tumor Location Causes Different Recurrence Patterns in Remnant Gastric Cancer
Journal of Gastric Cancer
2022 .10
-
Clinical features of recurrence after hepatic resection for early-stage hepatocellular carcinoma and long-term survival outcomes of patients with recurrence: A multi-institutional analysis
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
-
Outcomes and recurrence pattern after non-anatomic liver resection for solitary hepatocellular carcinomas
Annals of Hepato-Biliary-Pancreatic Surgery
2016 .02
-
Prognosis after intrahepatic recurrence in the patients who underwent curative resection for hepatocellular carcinoma
Annals of Hepato-Biliary-Pancreatic Surgery
2020 .11
-
Which Patients Should We Follow up beyond 5 Years after Definitive Therapy for Localized Renal Cell Carcinoma?
Cancer Research and Treatment
2015 .01
-
Prognosis according to the timing of recurrence in breast cancer
Annals of Surgical Treatment and Research
2023 .01
-
Identifying Predictive Factors for the Recurrence of Pediatric Intussusception
Pediatric Gastroenterology, Hepatology & Nutrition
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2016-514-001718472