지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.9
- 수록면
- 200 - 214 (15page)
이용수
이 논문의 연구 히스토리 (3)
2015
Transcriptional Profiling of an Attenuated Salmonella Typhimurium ptsI Mutant Strain Under Low-oxygen Conditions using Microarray Analysis
Sangyong Lim
,
Ah
,
eum Han
외 2명
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2015.09
학술저널
Transcriptional Profiling of an Attenuated Salmonella Typhimurium ptsI Mutant Strain Under Low-oxygen Conditions using Microarray Analysis
Sangyong Lim
,
Ah
,
eum Han
외 2명
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2015.09
학술저널
Microarray Analysis of Salmonella Typhimuruim ptsI Mutants Under Low Oxygen Conditions
Sangyong Lim
,
Dongho Kim
,
Hyunjin Yoon
한국미생물학회 학술대회논문집
2015.04
학술대회자료
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Salmonella causes a wide variety of diseases ranging from mild diarrhea to severe systemic infections, such as like typhoid fever, in multiple organisms, ranging from mice to humans. A lack of ptsI, which encodes the first component of phosphoenolpyruvate (PEP) : carbohydrate phosphotransferase system (PTS), is known to cause Salmonella Typhimurium attenuation; however, the mechanisms behind this have not yet been elucidated. In this study, a DNA microarray was performed to determine why the virulence of ptsI mutants is attenuated under low-oxygen conditions in which the ptsI expression is enhanced. Of 106 down-regulated genes, the most repressed were pdu and tdc genes, which are required for propanediol utilization and threonine and serine metabolism, respectively. In addition, half the flagellar genes were down-regulated in the ptsI mutant strain. Because pdu genes are induced during infection and Tdc products and flagellamediated motility are necessary for the invasion of S. Typhimurium, the invasive ability of ptsI mutants was examined. We found that ptsI mutation reduced the ability of S. Typhimurium to invade into host cells, suggesting that reduced expression of the pdu, tdc, and flagellar genes is involved in the attenuation of ptsI mutants.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Microarray Analysis of Salmonella Typhimuruim ptsI Mutants Under Low Oxygen Conditions
한국미생물학회 학술대회논문집
2015 .04
-
Investigation on PtSi/Si by spectroscopic ellipsometry
한국진공학회 학술발표회초록집
2016 .08
-
Immunogenicity and Safety of Salmonella Typhimurium phoBR Deleted Gene Mutant
한국미생물학회 학술대회논문집
2019 .04
-
Genomic Approaches for Understanding the Characteristics of Salmonella enterica subsp. enterica Serovar Typhimurium ST1120, Isolated from Swine Feces in Korea
Journal of Microbiology and Biotechnology
2017 .01
-
The Elongation Factor P Regulate Expression of Magnesium Transport Protein in Salmonella Typhimurium
한국미생물학회 학술대회논문집
2016 .04
-
Interleukin-10 Regulates the Bactericidal Activity against Salmonella Typhimurium Infection by Attenuating the Process of Phagocytosis
한국미생물학회 학술대회논문집
2022 .10
-
The Phase Variation of Salmonella Typhimurium Occurs under Phagocytosis in Mouse Macrophages
한국미생물학회 학술대회논문집
2017 .04
-
Separation, Purification and In Vitro Assays of Lipopolysaccharide in Salmonella Typhimurium
한국미생물학회 학술대회논문집
2020 .10
-
Inhibition of Salmonella Typhimurium Adhesion, and Invasion with Methyl Gallate
한국미생물학회 학술대회논문집
2020 .10
-
Understanding Virulence Regulation of Salmonella Typhimurium Using Proteomic Profiling of Outer Membrane Vesicles
한국미생물학회 학술대회논문집
2016 .04
-
Comparative Genomics Approaches to Understanding Virulence and Antimicrobial Resistance of Salmonella Typhimurium ST1539 Isolated from a Poultry Slaughterhouse in Korea
Journal of Microbiology and Biotechnology
2019 .01
-
Characterization of Bacteriophage-binding Receptors in Antibiotic-resistant Salmonella Typhimurium
한국미생물학회 학술대회논문집
2019 .04
-
Ubiquilin 1 Targets Invading Salmonella typhimurium to the Autophagy Pathway
한국미생물학회 학술대회논문집
2022 .10
-
Anti-tumor Effect of L-asparaginase Delivered by Salmonella typhimurium on Solid Tumors
한국미생물학회 학술대회논문집
2016 .04
-
Complete genome sequence of Salmonella enterica serovar Typhimurium MFDS1021937 isolated from food
미생물학회지
2024 .12
-
Action of plasma-activated acetic acid on the inactivation of Salmonella Typhimurium on stainless steel surfaces
한국진공학회 학술발표회초록집
2020 .08
-
Novel Approach of a Phage-Based Magnetoelastic Biosensor for the Detection of Salmonella enterica serovar Typhimurium in Soil
Journal of Microbiology and Biotechnology
2016 .12
-
Functional Role of MdsABC Pump in the Pathogenicity of Salmonella Typhimurium
한국미생물학회 학술대회논문집
2015 .04
-
Primary Transcriptome Analysis on Intra-macrophage Salmonella Typhimurium Defined a New Role of LeuO in Virulence Regulation
한국미생물학회 학술대회논문집
2022 .10
-
Primary Transcriptome Analysis on Intra-macrophage Salmonella Typhimurium Defined a New Role of LeuO in Virulence Regulation
한국미생물학회 학술대회논문집
2022 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2016-475-001942009