지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.93 No.2
- 발행연도
- 2017.8
- 수록면
- 76 - 81 (6page)
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초록· 키워드
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Purpose: The average rate of surgical site infections (SSIs) for laparoscopic cholecystectomy (LC) has been reported in the literature to be between 0.4% and 6.3%. Also, these recent reviews have concluded that a prophylactic antibiotics for elective LCs in low-risk patients is not useful, but there were no results in high-risk patients.
Methods: The aim of this study was to investigate the role of a single dose of first-generation cephalosporin as a prophylactic antibiotic for patients undergoing elective LC, regardless of patient risk. This randomized clinical trial was conducted from October 2013 to December 2014 by single surgeon at our hospital. Patients were randomized into two groups by following method. Odd-numbered patients (group A) received 1-g cefazolin intravenously within 30 minutes before incision, whereas even-numbered patients (group B) received normal saline intravenously instead of prophylactic antibiotics, with the aim of including 100 patients in each group. SSIs were recorded and compared between the groups.
Results: There were no differences in preoperative demographics and postoperative findings between the groups. There were no superficial and deep SSIs in either group, 9 cases of superficial seromas developed (4.5%) in the cohort: 4 in group A (4%) and 5 in group B (5%). There were no significant associations between SSIs and the use of prophylactic antibiotics in either group. Additionally, the high-risk group did not show a significantly increased rate of SSIs.
Conclusion: Based on our study, prophylactic antibiotics are not necessary in elective LC, regardless of patient risk.
Methods: The aim of this study was to investigate the role of a single dose of first-generation cephalosporin as a prophylactic antibiotic for patients undergoing elective LC, regardless of patient risk. This randomized clinical trial was conducted from October 2013 to December 2014 by single surgeon at our hospital. Patients were randomized into two groups by following method. Odd-numbered patients (group A) received 1-g cefazolin intravenously within 30 minutes before incision, whereas even-numbered patients (group B) received normal saline intravenously instead of prophylactic antibiotics, with the aim of including 100 patients in each group. SSIs were recorded and compared between the groups.
Results: There were no differences in preoperative demographics and postoperative findings between the groups. There were no superficial and deep SSIs in either group, 9 cases of superficial seromas developed (4.5%) in the cohort: 4 in group A (4%) and 5 in group B (5%). There were no significant associations between SSIs and the use of prophylactic antibiotics in either group. Additionally, the high-risk group did not show a significantly increased rate of SSIs.
Conclusion: Based on our study, prophylactic antibiotics are not necessary in elective LC, regardless of patient risk.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (19)
참고문헌 신청
[학술지(정기간행물)] - Chang WT / 2006 / The impact of prophylactic antibiotics on postoperative infection complication in elective laparoscopic cholecystectomy : a prospective randomized study / Am J Surg 191 : 721 ~ 725
[학술지(정기간행물)] - Biscione FM / 2007 / Comparison of the risk of surgical site infection after laparoscopic cholecystectomy and open cholecystectomy / Infect Control Hosp Epidemiol 28 : 1103 ~ 1106
[학술지(정기간행물)] - McGuckin M / 1999 / Infection and antimicrobial use in laparoscopic cholecystectomy / Infect Control Hosp Epidemiol 20 : 624 ~ 626
[학술지(정기간행물)] - Koc M / 2003 / A prospective randomized study of prophylactic antibiotics in elective laparoscopic cholecystectomy / Surg Endosc 17 : 1716 ~ 1718
[학술지(정기간행물)] - Mahatharadol V. / 2001 / A reevaluation of antibiotic prophylaxis in laparoscopic cholecystectomy : a randomized controlled trial / J Med Assoc Thai 84 : 105 ~ 108
[학술지(정기간행물)] - Biscione FM / 2007 / Comparison of the risk of surgical site infection after laparoscopic cholecystectomy and open cholecystectomy / Infect Control Hosp Epidemiol 28 : 1103 ~ 1106
[학술지(정기간행물)] - McGuckin M / 1999 / Infection and antimicrobial use in laparoscopic cholecystectomy / Infect Control Hosp Epidemiol 20 : 624 ~ 626
[학술지(정기간행물)] - Koc M / 2003 / A prospective randomized study of prophylactic antibiotics in elective laparoscopic cholecystectomy / Surg Endosc 17 : 1716 ~ 1718
[학술지(정기간행물)] - Mahatharadol V. / 2001 / A reevaluation of antibiotic prophylaxis in laparoscopic cholecystectomy : a randomized controlled trial / J Med Assoc Thai 84 : 105 ~ 108
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UCI(KEPA) : I410-ECN-0101-2018-514-001172776