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Antioxidant and anti-inflammatory activity on sea tangle (Laminaria japonica) adding vinegar
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다시마(Laminaria japonica) 첨가에 따라 제조된 식초의 항산화 및 항염증 활성 비교

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Type
Academic journal
Author
You Seong Ahn (광주대학교)
Journal
The Korean Society of Food Preservation Food Science and Preservation Vo.26 No.2 KCI Accredited Journals SCOPUS
Published
2019.4
Pages
211 - 218 (8page)
DOI
10.11002/kjfp.2019.26.2.211

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Antioxidant and anti-inflammatory activity on sea tangle (Laminaria japonica) adding vinegar
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The objective of this study was to evaluate the antioxidant and anti-inflammatory activity of vinegar with added sea tangle (Laminaria japonica) (VAST). To determine the antioxidant activity, DPPH and ABTS radical scavenging activity, reducing power, and total polyphenolic and flavonoid contents were evaluated. The anti-inflammatory activity was determined using lipopolysaccharide (LPS) induced macrophage (RAW 264.7). Finally, the antioxidant and anti-inflammatory activities of VAST were compared with those of vinegar without added sea tangle (VNAST). The antioxidant activity, total polyphenol content, and total flavonoid content were all higher in VAST than in VNAST. Moreover, neither VAST nor VNAST displayed toxicity toward RAW 246.7 cells at up to 200-fold dilution. In LPS-induced RAW 264.7 cells, VAST treatment significantly decreased the production of nitric oxide and inflammatory cytokine (TNF-α) compared with VNAST treatment. Overall, VAST showed exhibited superior antioxidant and anti-inflammatory activities compared with VNAST. These results clearly indicate that VAST has the potential for use as an anti-oxidant and anti-inflammatory agent in functional foods.

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