지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 174 - 179 (6page)
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Background/Aims: Small-intestinal bacterial overgrowth (SIBO) is a frequent finding in patients with irritable bowel syndrome (IBS). Many patients with IBS also have abnormal intestinal permeability, which is probably due to low-grade inflammation in the intestinal mucosa. Our aim was to verify the relationship between SIBO and small-intestinal permeability in IBS patients. Methods: A cohort of 38 IBS patients (20 women and 18 men; age range 16-70 years; mean age 40.2 years) with symptoms that fulfilled Rome-II criteria, and 12 healthy controls (5 women and 7 men; age range 25-52 years; mean age: 37.8 years) were recruited. All subjects underwent lactulose breath tests (LBTs) and intestinal permeability tests using the polyethylene glycol (PEG) 3350/400 retrieval ratio. Results: A positive LBT was found in 18.4% (7/38) of patients with IBS and 8.3% (1/12) of control subjects. Intestinal permeability was significantly increased in patients with IBS compared with the normal controls (0.82±0.09 vs 0.41±0.05 [mean±SD], respectively; p＜0.05). However, the intestinal permeability did not differ significantly between IBS patients with a positive LBT and those with a negative LBT (0.90±0.13 and 0.80±0.11, respectively; p＞0.05). Conclusions: Intestinal permeability was increased in patients with IBS, but this finding did not correlated with the occurrence of SIBO.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
American Gastroenterology Association / 2002 / American Gastroenterological Association medical position statement: irritable bowel syndrome / Gastroenterology 123 : 2105 ~
Berg RD / 1979 / Translocation of certain indigenous bacteria from the gastrointestinal tract to the mesenteric lymph nodes and other organs in a gnotobiotic mouse model / In
Bjarnson I / 1983 / Absorption of 51chromium-labeled ethylenediaminetetraacetate in inflammatory bowel disease / Gastroenterology 85 : 318 ~ 322
Dainese R / 1999 / Discrepancies between reported food intolerance and sensitization test findings in irritable bowel syndrome patients / Am J Gastroenterol 94 : 1892 ~ 1897
Dunlop SP / 2006 / Abnormal intestinal permeability in subgroups of diarrhea-predominant irritable bowel syndromes / Am J Gastroenterol 101 : 1288 ~ 1294
Berg RD / 1979 / Translocation of certain indigenous bacteria from the gastrointestinal tract to the mesenteric lymph nodes and other organs in a gnotobiotic mouse model / In
Bjarnson I / 1983 / Absorption of 51chromium-labeled ethylenediaminetetraacetate in inflammatory bowel disease / Gastroenterology 85 : 318 ~ 322
Dainese R / 1999 / Discrepancies between reported food intolerance and sensitization test findings in irritable bowel syndrome patients / Am J Gastroenterol 94 : 1892 ~ 1897
Dunlop SP / 2006 / Abnormal intestinal permeability in subgroups of diarrhea-predominant irritable bowel syndromes / Am J Gastroenterol 101 : 1288 ~ 1294
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