지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아소화기영양학회 Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제20권 제1호
- 발행연도
- 2017.1
- 수록면
- 41 - 46 (6page)
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초록· 키워드
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Purpose: Vitamin D deficiency is common in Crohn disease (CD). The aim of the study was to examine the prevalence of vitamin D deficiency and evaluate the association between vitamin D status and growth outcome in Korean pediatric CD patients.Methods: In this retrospective study, 17 children younger than 18 years old diagnosed with CD were enrolled and their serum 25-hydroxy vitamin D (25[OH]D) was checked between 2011 and 2015. We categorized the patients into two groups, Group 1 and Group 2. Group 1 included patients with serum 25(OH)D levels below 10 ng/mL, and Group 2 was for patients with a 25(OH)D serum levels between 10 ng/mL and 30 ng/mL. The z-scores for height (Htz), weight (Wtz), and body mass index (BMIz) were measured at baseline, 6 months, and 12 months. Results: The mean serum 25(OH)D levels of the total 65 CD patients and 17 enrolled patients were 15.64±6.9 ng/mL and 13.1±5.1 ng/mL , respectively. There was no correlation at the beginning of the study between vitamin D level and growth parameters (Htz, Wtz, BMIz) or other variables including laboratory data and Pediatric Crohn Disease Activity Index. The Htz, Wtz, and BMIz in Group 1 showed no significant improvement at 6 months and 12 months follow-up. In Group 2, Wtz and BMIz showed significant improvements sustained until 12 months of follow-up. Htz showed no significant improvement at 6 months but there was significant improvement at 12 months. Conclusion: It seems that baseline vitamin D status affects growth outcome in pediatric CD.
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참고문헌 (24)
참고문헌 신청
Alhagamhmad MH / 2012 / An update of the role of nutritional therapy in the management of Crohn's disease / J Gastroenterol 47 : 872 ~ 882
Ananthakrishnan AN / 2013 / Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease / Inflamm Bowel Dis 19 : 1921 ~ 1927
Andreassen H / 1998 / Regulators of calcium homeostasis and bone mineral density in patients with Crohn's disease / Scand J Gastroenterol 33 : 1087 ~ 1093
Choi HS / 2011 / Vitamin D insufficiency in Korea--a greater threat to younger generation: the Korea National Health and Nutrition Examination Survey (KNHANES) 2008 / J Clin
Holick MF / 2007 / Vitamin D deficiency / N Engl J Med 357 : 266 ~ 281
Ananthakrishnan AN / 2013 / Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease / Inflamm Bowel Dis 19 : 1921 ~ 1927
Andreassen H / 1998 / Regulators of calcium homeostasis and bone mineral density in patients with Crohn's disease / Scand J Gastroenterol 33 : 1087 ~ 1093
Choi HS / 2011 / Vitamin D insufficiency in Korea--a greater threat to younger generation: the Korea National Health and Nutrition Examination Survey (KNHANES) 2008 / J Clin
Holick MF / 2007 / Vitamin D deficiency / N Engl J Med 357 : 266 ~ 281
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