지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 185 - 191 (7page)
이용수
초록· 키워드
오류제보하기
Alcohol intake is known to affect various organs in the human body, causing reduction of salivation in the oral cavity. Hypo-salivation effect of alcohol is a common feature, but the mechanism in salivary glands is still poorly studied. Therefore, in this study, the changes in salivary secretion and water channel protein (aquaporin5, AQP5) in salivary glands of mice were investigated after ethanol administration. Animals were divided in to 4 groups with the control, 4 g/kg ethanol, 8 g/kg ethanol and 16 g/kg ethanol administration groups. One hour after ethanol administration, saliva was collected from the oral cavity, and the animals were killed and parotid and submandibular glands were extracted to analyze the histopathology, AQP5 immunihistochemistry and AQP5 protein level. According to the results, the salivation rate decreased irrespective of the ethanol dose in mice, and viscosities increased with increase in ethanol dose. However, there were no pathological changes in parotid and submandibular glands due to ethanol administration. Expression of AQP5 in parotid and submandibular glands decreased with increase ethanol administration These results indicate that the reduction of salivary secretion due to acute alcohol intake is closely related to decrease of the water channel protein such as AQP5 in parotid glands and submandibular glands, rather than the damage of salivary glands .
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Brooks PJ / 1997 / DDNA damage, DNA repair, and alcohol toxicity-a review / Alcohol Clin Exp Res 21:1073~1082
Carrard VC / 2004 / Quantification of silver-staining nucleolar organizer region in epithelial cells of tongue of mice after exposure to, or intake of, alcohol / Alcohol 34:233~238
Prestifilippo JP / 2009 / Role of the endocannabinoid system in ethanolinduced inhibition of salivary secretion / Alcohol Alcohol 44:443~448
Scott J / 1988 / Histological analysis of parotid and submandibular glands in chronic alcohol abuse: a necropsy study / J Clin Pathol 41:837~840
Simanowski UA / 2001 / Increased rectal cell proliferation following alcohol abuse / Gut 49:418~422
Carrard VC / 2004 / Quantification of silver-staining nucleolar organizer region in epithelial cells of tongue of mice after exposure to, or intake of, alcohol / Alcohol 34:233~238
Prestifilippo JP / 2009 / Role of the endocannabinoid system in ethanolinduced inhibition of salivary secretion / Alcohol Alcohol 44:443~448
Scott J / 1988 / Histological analysis of parotid and submandibular glands in chronic alcohol abuse: a necropsy study / J Clin Pathol 41:837~840
Simanowski UA / 2001 / Increased rectal cell proliferation following alcohol abuse / Gut 49:418~422
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Comparative Morphological Study on Parotid and Submandibular Salivary Glands in Ovariectomized Rats
치위생과학회지
2022 .06
-
Assessment of Age-Related Dimensions of the Salivary and Thyroid Glands Using Three-Dimensional Computed Tomography in Children
대한이비인후-두경부외과학회지
2016 .01
-
Application of Developmental Principles for Functional Regeneration of Salivary Glands
해부·생물인류학
2019 .09
-
Effects of Cinnamaldehyde on Salivary Gland Tissue in Xerostomia Model
대한의생명과학회지
2020 .06
-
Induction of Anti-Aquaporin 5 Autoantibody Production by Immunization with a Peptide Derived from the Aquaporin of Prevotella melaninogenica Leads to Reduced Salivary Flow in Mice
Immune Network
2021 .10
-
Rabbit submandibular salivary gland replantation
대한구강악안면외과학회지
2017 .01
-
생선 이물에 의한 타석증 1예
대한이비인후-두경부외과학회지
2016 .01
-
Optimal Treatment for the High-Risk Salivary Gland Cancer
Clinical and Experimental Otorhinolaryngology
2020 .01
-
Study on Changes in Endogenous Stem Cells in the Salivary Gland of Streptozotocin-induced Diabetic Rats
International Journal of Oral Biology
2017 .01
-
Toothache Caused by Sialolithiasis of the Submandibular Gland
Journal of Oral Medicine and Pain
2018 .09
-
Effect of Gamma Irradiation on the Function of Mouse Salivary Glands
한국실험동물학회 학술발표대회 논문집
2016 .02
-
Metachronous malignant tumors in ipsilateral salivary glands
Archives of craniofacial surgery : ACFS
2019 .01
-
Accuracy of Ultrasound-Guided and Non-ultrasound-Guided Botulinum Toxin Injection Into Cadaver Salivary Glands
Annals of Rehabilitation Medicine
2017 .01
-
악하선에 발생한 낭샘암종
대한 두경부 종양 학술지
2015 .01
-
Salivary Duct Carcinoma of the Deep Lobe of the Parotid Gland: A Rare Clinical Finding
Archives of plastic surgery : APS
2016 .01
-
이하선에서 기원한 다형성 저등급 선암종 1예
임상이비인후과
2015 .06
-
Expression patterns of Rho-associated protein kinase signaling pathway-related genes in mouse submandibular glands
International Journal of Oral Biology
2021 .01
-
Alcohol ingestion reduced acetylcholine-binding protein in the submandibular gland of the rat
Oral Biology Research
2017 .01
-
Effectiveness of ultrasonography and shear wave sonoelastography in Sjogren syndrome with salivary gland involvement
ULTRASONOGRAPHY
2021 .10
-
이하선에 발생한 낭선암종 1예
대한이비인후-두경부외과학회지
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0