지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제3권 제2호
- 발행연도
- 2015.1
- 수록면
- 159 - 163 (5page)
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초록· 키워드
오류제보하기
Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg-Strauss syndrome, is a rare systemic necrotizing vasculitis affecting small- to medium-sized vessels. EGPA is associated with severe asthma and eosinophilia. The most frequently involved organs are skin and peripheral nerves; however, EGPA may involve other organs, such as the gastrointestinal tract, kidney, and heart. Antineutrophil cytoplasm antibodies (ANCAs)-related abnormal immune reactions are known to be associated with EGPA, but only 30%–40% of patients have a positive marker of ANCA. ANCA-negative patients are at higher risk of cardiac involvement than ANCA-positive patients. Cardiac involvement is one of the leading causes of mortality and could be resistant to conventional treatment. Early treatment with steroid plus cyclophosphamide is important because it could give chances of restoration of cardiac function. For patients undergoing heart transplantation, we should consider the severity of cardiac disease and the presence of systemic diseases, including vasculitis. Here, we report a case of a 25-year-old EGPA patient with cardiac involvement who eventually received heart transplantation for progressive heart failure, although treated with systemic corticosteroid with cyclophosphamide. EGPA patients undergoing heart transplantion are rarely reported worldwide, and this is the first case report in Korea.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Abril A / 2011 / Churg-strauss syndrome : an update / Curr Rheumatol Rep 13 : 489 ~ 495
Castel MA / 2011 / Primary immunosuppression and outcome differences after heart transplantation : tacrolimus versus cyclosporine / Transplant Proc 43 : 2244 ~ 2246
Comarmond C / 2013 / Eosinophilic granulomatosis with polyangiitis(Churg-Strauss) : clinical characteristics and long-term followup of the 383 patients enrolled in the Frenc
Corradi D / 2009 / Postpartum Churg-Strauss syndrome with severe cardiac involvement : description of a case and review of the literature / Clin Rheumatol 28 : 739 ~ 743
Grimm M / 2006 / Superior prevention of acute rejection by tacrolimus vs. cyclosporine in heart transplant recipients: a large European trial / Am J Transplant 6 : 1387 ~ 13
Castel MA / 2011 / Primary immunosuppression and outcome differences after heart transplantation : tacrolimus versus cyclosporine / Transplant Proc 43 : 2244 ~ 2246
Comarmond C / 2013 / Eosinophilic granulomatosis with polyangiitis(Churg-Strauss) : clinical characteristics and long-term followup of the 383 patients enrolled in the Frenc
Corradi D / 2009 / Postpartum Churg-Strauss syndrome with severe cardiac involvement : description of a case and review of the literature / Clin Rheumatol 28 : 739 ~ 743
Grimm M / 2006 / Superior prevention of acute rejection by tacrolimus vs. cyclosporine in heart transplant recipients: a large European trial / Am J Transplant 6 : 1387 ~ 13
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