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학술저널
저자정보
Bae, Seung Il (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) Jang, Jong Geol (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) Kim, Hun Tae (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) Ahn, Hee Yun (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) Kim, Min Jung (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) Kim, Hyun Je (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) Lee, Choong Ki (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) Hong, Young Hoon (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University)
저널정보
영남대학교 의과대학 영남의대학술지 영남의대학술지 제32권 제2호
발행연도
2015.1
수록면
127 - 131 (5page)

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Churg-Strauss syndrome (CSS) is a necrotizing vasculitis with extra-, peri-vascular eosinophilic infiltration. Chronic symmetric polyarthritis with the presence of rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibody are the mainstay of rheumatoid arthritis (RA) diagnosis. Mononeuritis multiplex is a peripheral neuropathy involving more than 2 separate nerve areas. A 62-year-old male patient was referred for left foot drop and polyarthritis of both hands and feet for 4 months. During evaluation, mononeuritis multiplex was detected on nerve conduction study and electromyography tests: vasculitis with neutrophil, eosinophil, and lymphocyte infiltration on peroneal nerve biopsy. A positive response to methacholin and bronchodilator was observed on the pulmonary function test. Radiologic tests showed peri-articular soft tissue swelling and osteopenia on both hand and foot. Marked peripheral eosinophilia, high RF, and positive perinuclear anti-neutrophil cytoplasmic antibody were detected on blood tests. Here, we report on a patient with overlap syndrome of CSS and RA with review of the relevant literature, from which a few references to overlap syndrome of CSS and RA were available.

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