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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 153 - 157 (5page)
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Background and Purpose The objective of this study was to determine if the MOXO visualandvocal-distractors-based continuous performance test distinguishes patients with attentiondeficit hyperactivity disorder (ADHD) and neurofibromatosis type 1 (NF1) from those withoutNF1. Methods Thirty-five patients (16 males; mean age 9.91 years) attending a multidisciplinaryNF1 clinic completed the MOXO test. The findings were compared to 532 healthy age-matchedstandardized control subjects (285 males) without ADHD. Results The overall performance in the MOXO text was significantly worse in the NF1group than in controls (p<0.01), but no group-specific pattern was identified. Impulsivity andhyperactivity were significantly more prominent in males than females (p<0.01). Comparedto controls, the NF1 group exhibited significantly more failures to respond to target stimuli inthe presence of visual distractors. Conclusions MOXO scores are abnormal in patients with NF1, but the test cannot differentiatebetween NF1 with ADHD characteristics and ADHD. The test highlights sex differences inADHD characteristics in NF1. Overreactivity to visual distractors may form part of the attentiondeficit in NF1.
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참고문헌 (30)
참고문헌 신청
Williams VC / 2009 / Neurofibromatosis type 1 revisited / Pediatrics 123:124~133
Rauen KA / 2013 / The RASopathies / Annu Rev Genomics Hum Genet 14:355~369
Acosta MT / 2012 / The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research / Am J Med Genet A 158A:2225~2232
Payne JM / 2011 / Assessment of executive function and attention in children with neurofibromatosis type 1: relationships between cognitive measures and real-world behavior / Child Neuropsychol 17:313~329
Centers for Disease Control and Prevention / Attention Deficit Hyperactivity Disorder (ADHD)
Rauen KA / 2013 / The RASopathies / Annu Rev Genomics Hum Genet 14:355~369
Acosta MT / 2012 / The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research / Am J Med Genet A 158A:2225~2232
Payne JM / 2011 / Assessment of executive function and attention in children with neurofibromatosis type 1: relationships between cognitive measures and real-world behavior / Child Neuropsychol 17:313~329
Centers for Disease Control and Prevention / Attention Deficit Hyperactivity Disorder (ADHD)
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