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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 170 - 174 (5page)
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초록· 키워드
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Background and Purpose A thick corpus callosum (TCC) can be associated with a very grave outcome in fetuses, but its clinical presentation in older children seems to be markedly different.
Methods The corpus callosum (CC) was defined as thick based on observations and impressions. We reviewed cases of children who were diagnosed as TCC based on brain magnetic resonance imaging (MRI) studies. The pertinent clinical data of these children were collected, and their CCs were measured.
Results Out of 2,552 brain MRI images, those of 37 children were initially considered as showing a TCC. Those initial imaging were reviewed by an experienced neuroradiologist, who confirmed the diagnosis in 34 children (1.3%): 13 had neurofibromatosis-1 (NF-1), 9 had epilepsy, 3 had macrocephaly capillary malformation (MCM) syndrome, 3 had autistic spectrum disorder, 1 had a Chiari-1 malformation, and 1 had increased head circumference. No specific neurologic disorder could be defined in seven children. The measured thickness of the CC in these children was comparable to those published in the literature for adults.
Conclusions A TCC is a rare brain malformation that can be found in neuropathologies with apparently diverse pathognomonic mechanisms, such as NF-1 and MCM. It is not necessarily associated with life-threatening conditions, instead being a relatively benign finding, different in nature from that reported in fetuses.
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참고문헌 (24)
참고문헌 신청
Allen LS / 1991 / Sex differences in the corpus callosum of the living human being / J Neurosci 11 : 933 ~ 942
Bayram E / 2014 / Comparison of cranial magnetic resonance imaging findings and clinical features in patients with corpus callosum abnormalities / Neuropediatrics 45 : 30 ~ 3
Bermudez P / 2001 / Sexual dimorphism in the corpus callosum:methodological considerations in MRI morphometry / Neuroimage 13 (6 Pt 1) : 1121 ~ 1130
Boger-Megiddo I / 2006 / Corpus callosum morphometrics in young children with autism spectrum disorder / J Autism Dev Disord 36 : 733 ~ 739
Booth R / 2011 / Connectivity and the corpus callosum in autism spectrum conditions: insights from comparison of autism and callosal agenesis / Prog Brain Res 189 : 303 ~ 31
Bayram E / 2014 / Comparison of cranial magnetic resonance imaging findings and clinical features in patients with corpus callosum abnormalities / Neuropediatrics 45 : 30 ~ 3
Bermudez P / 2001 / Sexual dimorphism in the corpus callosum:methodological considerations in MRI morphometry / Neuroimage 13 (6 Pt 1) : 1121 ~ 1130
Boger-Megiddo I / 2006 / Corpus callosum morphometrics in young children with autism spectrum disorder / J Autism Dev Disord 36 : 733 ~ 739
Booth R / 2011 / Connectivity and the corpus callosum in autism spectrum conditions: insights from comparison of autism and callosal agenesis / Prog Brain Res 189 : 303 ~ 31
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