지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 341 - 348 (8page)
이용수
초록· 키워드
오류제보하기
ObjectiveaaComprehensive neuropsychological tests are important in the diagnosis and follow-up of patients with MCI; however, most were developed without consideration of illiteracy. We developed the Literacy Independent Cognitive Assessment (LICA) as a comprehensive neuropsychological assessment battery applicable to older adults who are either literate or illiterate. This study aimed to assess the reliability and validity of the LICA for diagnosis of MCI.
MethodsaaNormal controls (n=634) and patients with MCI (n=128) were recruited from 13 centers were included in this study. Participants were divided into illiterate or literate groups, based on their performance on a brief reading and writing test. The LICA, Korean Mini-Mental State Examination (K-MMSE), and Seoul Neuropsychological Screening Battery (SNSB) were administered.
ResultsaaTotal LICA scores distinguished MCI patients from controls (p<0.001). They were closely and positively correlated to the KMMSE scores (r=0.632, p<0.001) but negatively correlated to clinical dementia rating (CDR) (r=-0.358, p<0.001) and CDR sum of boxes (r=-0.339, p<0.001). Area under the receiver operating characteristic curve for patients with MCI by total LICA score was 0.827 (0.783- 0.870), superior to that presented by the K-MMSE. For the classification of MCI subtypes, inter-method reliability of LICA with the SNSB was good (κ 0.773; 0.679–0.867, p<0.001).
ConclusionaaThe results of this study show that the LICA may be reliably used to distinguish MCI patients from cognitively intact adults, to identify MCI subtypes and monitor progression toward dementia, regardless of illiteracy.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Albert MS / 2011 / The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association work
Baiyewu O / 2005 / The Stick Design test: a new measure of visuoconstructional ability / J Int Neuropsychol Soc 11 : 598 ~ 605
Benson DF / 1970 / Disturbances in constructional ability / Cortex 6 : 19 ~ 46
Bruscoli M / 2004 / Is MCI really just early dementia? A systematic review of conversion studies / Int Psychogeriatr 16 : 129 ~ 140
Busse A / 2006 / Mild cognitive impairment: long-term course of four clinical subtypes / Neurology 67 : 2176 ~ 2185
Baiyewu O / 2005 / The Stick Design test: a new measure of visuoconstructional ability / J Int Neuropsychol Soc 11 : 598 ~ 605
Benson DF / 1970 / Disturbances in constructional ability / Cortex 6 : 19 ~ 46
Bruscoli M / 2004 / Is MCI really just early dementia? A systematic review of conversion studies / Int Psychogeriatr 16 : 129 ~ 140
Busse A / 2006 / Mild cognitive impairment: long-term course of four clinical subtypes / Neurology 67 : 2176 ~ 2185
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