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자료유형
학술저널
저자정보
저널정보
대한암학회 Cancer Research and Treatment Cancer Research and Treatment 제47권 제4호
발행연도
2015.1
수록면
569 - 574 (6page)

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Purpose Primary central nervous system lymphoma (PCNSL) is an uncommon brain tumor accountingfor 2%-5% of all primary brain tumors. Few population-based analyses of survival forpatients with PCNSL have been conducted, particularly in Asian countries. Materials and MethodsUsing the Korea National Cancer Incidence Database, 1,062 cases of PCNSL newly diagnosedfrom 1999 to 2009 were analyzed. The crude rate, age-standardized rate (ASR), andannual percent change were calculated. To estimate the observed survival, we restrictedthe data to between 1999 and 2007 and followed the cases until December 2010. Theoverall survival was estimated using the Kaplan-Meier method, and piecewise Poissonregression model. ResultsThe ASR for PCNSL between 1999 and 2009 was 0.17 per 100,000, and the annualpercent change from 1999 to 2009 was 8.8% (p < 0.001). The ASR of males was higherthan that of females, and the older groups (60s or over) showed the largest increase inincidence rates. For all ages, the five-year survival from PCNSL was 29.9% between 1999and 2007. Survival from PCNSL is known to show strong association with age at diagnosis. ConclusionThese results are similar to those of previous studies. Our findings may be helpful to cliniciansand patients in determining long-term prognoses for PCNSL.

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