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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 506 - 509 (4page)
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초록· 키워드
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Background: The Spectra Optia (SPO) is a novel continuous-flow centrifugal apheresis system based on the COBE Spectra (CSP) platform. There have been few attempts to validate the advantages of the SPO. We performed a retrospective study comparing the two cell separators for therapeutic plasma exchange (TPE) procedures in kidney transplant (KT) patients and seeing efficacy and safety.
Methods: We analyzed 720 TPE procedures performed between August 2012 and July 2014. Procedures included desensitization TPE before KT and TPE for the management of acute and chronic antibody-mediated graft rejection. Demographic characteristics, operational TPE variables, and laboratory data were analyzed.
Results: Demographic characteristics for the SPO (n=389) and CSP (n=331) groups did not differ significantly. The procedure time to exchange one plasma volume was 94.2±10.3 min in the SPO group and 100.4±11.2 min in the CSP group (P<0.001). The plasma removal efficiency (PRE) was 92.5±4.9% in the SPO group and 83.2±3.7% in the CSP group (P<0.001). There were no significant differences across the two apheresis systems for changes in hematologic parameters.
Conclusions: Compared with the CSP, the SPO was associated with an improved PRE and a shorter procedure time to exchange one plasma volume. Our results in KT patients show that the SPO is superior to the CSP in TPE procedures.
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등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
De Silvestro G / 2004 / National survey of apheresis activity in Italy(2000) / Transfus Apher Sci 30 : 61 ~ 71
Hequet O / 2014 / Comparison of plasma exchange performances between Spectra Optia and COBE Spectra apheresis systems in repeated procedures considering variability and using
Kenmochi T / 2008 / Results of kidney transplantation from ABO-incompatible living donors in a single institution / Transplant Proc 40 : 2289 ~ 2291
Nadler SB / 1962 / Prediction of blood volume in normal human adults / Surgery 51 : 224 ~ 232
Norda R / 2003 / Therapeutic apheresis in Sweden: update of epidemiology and adverse events / Transfus Apher Sci 29 : 159 ~ 166
Hequet O / 2014 / Comparison of plasma exchange performances between Spectra Optia and COBE Spectra apheresis systems in repeated procedures considering variability and using
Kenmochi T / 2008 / Results of kidney transplantation from ABO-incompatible living donors in a single institution / Transplant Proc 40 : 2289 ~ 2291
Nadler SB / 1962 / Prediction of blood volume in normal human adults / Surgery 51 : 224 ~ 232
Norda R / 2003 / Therapeutic apheresis in Sweden: update of epidemiology and adverse events / Transfus Apher Sci 29 : 159 ~ 166
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