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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 371 - 374 (4page)
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Dear Editor, Cold agglutinin is an autoantibody that causes autoimmune hemolytic anemia by binding to I/i carbohydrate antigens on the red blood cell (RBC) surface [1]. While RBC agglutination causes clinical symptoms of hemolytic anemia, agglutination caused by cold agglutinin is a notorious pre-analytical and analytical factor that leads to spurious automated complete blood count (CBC) results [2]. Although RBC agglutination falsely increases mean corpuscular volume (MCV), effects of cold agglutinin on other CBC parameters have not been widely studied [3, 4]. The effects of cold agglutinin on CBC results have been evaluated mainly for a limited number of parameters, on old versions of automated CBC analyzers [5, 6], which have undergone remarkable technical improvements in the last decade. We present a case of chronic cold agglutinin disease, and report the effects of cold agglutinin on CBC parameters based on whole blood samples comparatively analyzed by four automated CBC analyzers commonly used in current clinical laboratories.
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참고문헌 (10)
참고문헌 신청
Swiecicki PL / 2013 / Cold agglutinin disease / Blood 122:1114~1121
Zandecki M / 2007 / Spurious counts and spurious results on haematology analysers: a review. Part II: white blood cells, red blood cells, haemoglobin, red cell indices and reticulocytes / Int J Lab Hematol 29:21~41
Ercan S / 2014 / 70-year old female patient with mismatch between hematocrit and hemoglobin values: the effects of cold agglutinin on complete blood count / Biochem Med 24:391~395
Gene Gulati / 2013 / Purpose and Criteria for Blood Smear Scan, Blood Smear Examination, and Blood Smear Review / Annals of Laboratory Medicine 33(1):1~7
1992 / Medicare, Medicaid and CLIA programs; regulations implementing the Clinical Laboratory Improvement Amendments of 1988 (CLIA)--HCFA. Final rule with comment period / Fed Regist 57:7002~7186
Zandecki M / 2007 / Spurious counts and spurious results on haematology analysers: a review. Part II: white blood cells, red blood cells, haemoglobin, red cell indices and reticulocytes / Int J Lab Hematol 29:21~41
Ercan S / 2014 / 70-year old female patient with mismatch between hematocrit and hemoglobin values: the effects of cold agglutinin on complete blood count / Biochem Med 24:391~395
Gene Gulati / 2013 / Purpose and Criteria for Blood Smear Scan, Blood Smear Examination, and Blood Smear Review / Annals of Laboratory Medicine 33(1):1~7
1992 / Medicare, Medicaid and CLIA programs; regulations implementing the Clinical Laboratory Improvement Amendments of 1988 (CLIA)--HCFA. Final rule with comment period / Fed Regist 57:7002~7186
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