지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.10
- 수록면
- 269 - 277 (9page)
- DOI
- 10.47429/lmo.2022.12.4.269
이용수
초록· 키워드
오류제보하기
Background: Complete blood count (CBC) and white blood cell (WBC) differential are essential tests for various diseases. Related to this, the Mindray BC-6200 automated hematology analyzer (BC-6200, Mindray Bio-Medical Electronics Co., Ltd, China) was recently launched in clinical laboratories. This study aimed to evaluate the analytical and flagging performance of BC-6200.
Methods: Using 688 whole blood samples, the precision and carryover of 12 CBC parameters were evaluated with BC-6200 according to the Clinical and Laboratory Standards Institute (CLSI) guidelines EP15-A3 and H26-A2, respectively. 11 CBC parameters of BC-6200 were compared with Sysmex XE-2100 (XE-2100, Sysmex Corporation, Japan) according to the CLSI guideline EP09c. To evaluate the flagging performance for blasts, immature granulocytes (IG), atypical lymphocytes (AL), and nucleated red blood cells (NRBC) of BC-6200, sensitivity, specificity, and efficiency to manual counts were estimated according to the CLSI guideline H20-A2.
Results: Precisions of WBC, red blood cells (RBC), hemoglobin (Hb), hematocrit (Hct), and platelets (PLT) were acceptable. Carryover was less than 1% in WBC, RBC, Hb, Hct, and PLT. In WBC differentials, BC-6200 and XE-2100 showed very high correlations, except for basophils. Flagging performances of BC-6200 showed excellent results in efficiency; 91.4% for blasts, 79.4% for IG, 75.5% for AL, and 98.6% for NRBC.
Conclusions: The analytical performances of BC-6200 were acceptable and comparable with those of XE-2100. The flagging performance was also comparable with that of manual counts. BC-6200 would be a competent instrument in clinical laboratories
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