메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Objective:Dysregulation in one-carbon metabolism has been associated with cognitive impairment in western studies. However there has been no previous Korean study on this issue. This study aimed to investigate the associations between the major components of the one-carbon metabolism and cognitive impairment in a Korean community population. Methods:732 people aged 65 or over were recruited. Serum levels of folate, vitamin B12 and homocysteine were assayed. Cognitive function was measured by Korean version of Mini-Mental State Examination (MMSE-K), and cognitive impairment was defined as MMSE-K≤20. Potential confounding/mediating factors were formally assessed: demographic data, disability, depression, alcohol comsumption, physical activity, vascular risk factors, and serum creatinine level. Results:Cognitive impairment was significantly associated with lower folate and higher homocysteine levels independent of confounding or mediating factors, while the association with vitamin B12 was not. Conclusions:The present findings support the role for folate and homocysteine in the etiology of cognitive impairment in Korean elders as well.

목차

등록된 정보가 없습니다.

참고문헌 (9)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0