지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 8 - 14 (7page)
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이 논문의 연구 히스토리 (2)
2016
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초록· 키워드
오류제보하기
Granulosa cells surround the oocyte within the ovarian follicle and play an essential role in creatingconditions required for oocyte as well as follicular development. The current study was conductedto examine the gene expression profile of mouse ovaries during the primordial to primary follicletransition process. Total RNAs from mouse ovaries on day 5 and day 12 were synthesized cDNAusing annealing control primers. The DEGs were cloned and their identities were analyzed byBLAST search. The Plekha5 and Anxa11 were highly expressed in primary follicle stage. Bycontrast, their expression was increased in granulosa cells at the primary follicle stage. We havesuccessfully discovered a list of genes expressed in day 5 and day 12 ovaries and confirmed thatsome of them are differentially expressed in PMF and/or PRI. This is a spatial-temporal regulatorymechanism on the ovarian folliculogenesis through membrane fusion. The gene expression profilefrom the current study would provide insight for future study on the mechanism(s) involved inprimordial-primary follicular transition. This will provide information for identification of themechanism of ovarian dysfunction.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Richards JS / 2001 / Perspective : the ovarian follicle-a perspective in 2001 / Endocrinology 142:2184~2193
Fortune JE / 2000 / The primordial to primary follicle transition / Mol Cell Endocrinol 163:53~60
Fortune JE / 2003 / The early stages of follicular development : activation of primordial follicles and growth of preantral follicles / Anim Reprod Sci 78:135~163
Hillier SG / 2001 / Gonadotropic control of ovarian follicular growth and development / Mol Cell Endocrinol 179:39~46
Ge W / 2005 / Intrafollicular paracrine communication in the zebrafish ovary : The state of the art of an emerging model for the study of vertebrate folliculogenesis / Mol Cell Endocrinol 237:1~10
Fortune JE / 2000 / The primordial to primary follicle transition / Mol Cell Endocrinol 163:53~60
Fortune JE / 2003 / The early stages of follicular development : activation of primordial follicles and growth of preantral follicles / Anim Reprod Sci 78:135~163
Hillier SG / 2001 / Gonadotropic control of ovarian follicular growth and development / Mol Cell Endocrinol 179:39~46
Ge W / 2005 / Intrafollicular paracrine communication in the zebrafish ovary : The state of the art of an emerging model for the study of vertebrate folliculogenesis / Mol Cell Endocrinol 237:1~10
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