지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 18 - 22 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: The previous reports regarding VUR resolution were not precise due to early frequent surgical intervention. We evaluated the spontaneous resolution (SR) rate and the incidence of new renal scars in primary VUR, focusing on severe reflux.
Methods: Medical records of 334 patients with primary VUR who were on medical prophylaxis without surgery for 1 to 9 years, were retrospectively reviewed. Medical prophylaxis was initiated with low-dose antibiotic prophylaxis or probiotics. Ra dioisotope cystourethrography was performed every 1 to 3 years until SR of reflux.
New renal scar was evaluated with follow-up 99m Tc DMSA renal scan.
Results: The SR rates decreased as VUR grades were getting higher (P=0.00).
The overall and annual SR were 58.4% and 14.9%/yr in grade IV reflux and 37.5% and 9.3%/yr in grade V reflux. The median times of SR were 38 months in grade IV reflux and 66 months in grade V reflux. The probable SR rates in grade IV and V reflux were 7.8% and 8.9% in the 1st year, 46.0% and 30.8% in the 3rd year and 74.4% and 64.4% in the 5th year. The incidences of new renal scars between low to moderate reflux and severe reflux showed no significant difference (P=0.32).
Conclusion: The SR rates of severe primary VUR were higher than previously re ported and most new renal scars were focal and mild.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Tamminen-Mobius T / 1992 / Cessation of vesicoureteral reflux for 5 years in infants and children allocated to medical treatment. The International Reflux Study in Children / The Journal of Urology 148:1662~1666
Elder JS / 1997 / Pediatric Vesicoureteral Reflux Guidelines Panel summary report on the management of primary vesicoureteral reflux in children / The Journal of Urology 157:1846~1851
Kliegman R. / 2011 / Vesicoureteral Reflux / Elsevier Science & Technology
Smellie JM / 2001 / Outcome at 10 years of severe vesicoureteric reflux managed medically : Report of the International Reflux Study in Children / The Journal of Pediatrics 139:656~663
Schwab CW Jr. / 2002 / Spontaneous resolution of vesicoureteral reflux : a 15-year perspective / The Journal of Urology 168:2594~2599
Elder JS / 1997 / Pediatric Vesicoureteral Reflux Guidelines Panel summary report on the management of primary vesicoureteral reflux in children / The Journal of Urology 157:1846~1851
Kliegman R. / 2011 / Vesicoureteral Reflux / Elsevier Science & Technology
Smellie JM / 2001 / Outcome at 10 years of severe vesicoureteric reflux managed medically : Report of the International Reflux Study in Children / The Journal of Pediatrics 139:656~663
Schwab CW Jr. / 2002 / Spontaneous resolution of vesicoureteral reflux : a 15-year perspective / The Journal of Urology 168:2594~2599
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