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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 31 - 38 (8page)
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초록· 키워드
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Purpose: We evaluated the long-term results of endoscopic Deflux® injection for treating vesicoureteral reflux (VUR) in children.
Methods: Between September 2004 and September 2014, 243 children (137 boys and 106 girls) with a mean age of 53 months underwent Deflux® injection.
Our clinical protocol included radionuclide voiding cystography (RNC) at postoperative 3 months, 1 year and 3 years to assess the VUR resolution.
Results: The cure rates at 3 months, 1 year, and 3 years by patients were 70.8%, 64.3%, and 65.6% for the total patients and 79.2%, 75.2%, and 76.4%, for the ureters, respectively. The recurrence rate of postoperative febrile urinary tract infection (UTI) was 20% in patients without VUR at postoperative 1 year. Twenty patients undergoing ureteroneocystostomy (UNC) significantly had younger age (P=0.003), higher VUR grade (P<0.001), and lower success rates of Deflux® injection (P<0.05). On univariate analysis, older age (P=0.014) and lower grade of VUR (P= 0.031) were the significant predictors of a successful outcome. But there was none on multivariate analysis. Younger age, especially age of 0-12 month-old, was the only significant predictor of postoperative febrile UTI recurrence on both univariate and multivariate analysis.
Conclusion: Deflux® injection is efficacious with a low complication rate for the anti-reflux procedure in children. There is low recurrence rate of UTI though VUR persists, and high probability of no VUR at 3 years if no VUR at 1 year. It is recommendable not to perform follow-up RNC at 3 years routinely if no VUR at 1 year.
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등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Al-Hunayan AA / 2002 / Outcome of endoscopic treatment for vesicoureteral reflux in children using polydimethylsiloxane / J Urol 168 : 2181 ~ 2183
Capozza N / 2002 / Dextranomer/hyaluronic acid copolymer implantation for vesico-ureteral reflux : a randomized comparison with antibiotic prophylaxis / J Pediatr 140 : 230
Chertin B / 2002 / Endoscopic treatment of vesicoureteral reflux : 11 to 17 years of followup / J Urol 167 : 1443 ~ 1446
Dodat H / 2004 / Vesicoureteric reflux in children: long-term results of endoscopic treatment by Macroplastique injection / Prog Urol 14 : 380 ~ 384
Elder JS / 2006 / Endoscopic therapy for vesicoureteral reflux: a metaanalysis. I. Reflux resolution and urinary tract infection / J Urol 175 : 716 ~ 722
Capozza N / 2002 / Dextranomer/hyaluronic acid copolymer implantation for vesico-ureteral reflux : a randomized comparison with antibiotic prophylaxis / J Pediatr 140 : 230
Chertin B / 2002 / Endoscopic treatment of vesicoureteral reflux : 11 to 17 years of followup / J Urol 167 : 1443 ~ 1446
Dodat H / 2004 / Vesicoureteric reflux in children: long-term results of endoscopic treatment by Macroplastique injection / Prog Urol 14 : 380 ~ 384
Elder JS / 2006 / Endoscopic therapy for vesicoureteral reflux: a metaanalysis. I. Reflux resolution and urinary tract infection / J Urol 175 : 716 ~ 722
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