지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.1
- 수록면
- 54 - 58 (5page)
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초록· 키워드
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Purpose: To evaluate the influence of prostate volume on the changes of International Prostate Symptoms
Score (IPSS) and other clinical parameters in men with lower urinary tract symptoms (LUTS) undergoing tamsulosin
treatment.
Materials and Methods: Patients were evaluated initially by IPSS/QoL questionnaire, digital rectal examination
(DRE), transrectal ultrasonography (TRUS), urinalysis, serum prostate-specific antigen (PSA), maximal urine flow
rate (Qmax) and post-void residual urine (PVR). Patients were grouped according to baseline prostate volume (PV):
PV＜20 ml (group A), 20 ml≤PV＜30 ml (group B), 30 ml≤PV＜40 ml (group C), PV≥40 ml (group D). All
the patients were given tamsulosin 0.2 mg per day. After 8 weeks of tamsulosin treatment, clinical efficacy was
determined by changes of IPSS/QoL scores, Qmax and PVR volumes.
Results: Overall 672 patients were enrolled initially and 580 patients have finished the protocol. After treatment,
total IPSS score was decreased by 6.2 point (31.7%) and Qmax was increased by 1.8ml/sec (29.7%). When clinical
outcomes were compared according to the different PV groups, there were no statistically significant differences
among groups except significant Qmax changes between group B and D.
Conclusion: Clinical efficacy of short term tamsulosin medication is not affected by the prostate volume. It
may be necessary that the results of this study should be confirmed in further long term follow-ups. (J. Korean
Continence Society 2007;11:54-58)
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
/ / Abrams P. In support of pressure-flow studies for evaluatingmen with lower urinary tract symptoms. Urology 1994 : 153 ~ 5
/ / Kontturi MJ. Urodynamic effects of finasteridein the treatment of bladder outlet obstruction due to benignprostatic hyperplasia. J Urol 1993 : 342 ~ 4
/ / The response to alpha blockadein benign prostatic hyperplasia is related to the percentarea density of prostate smooth muscle : 297 ~ 307
/ / Yaksh TL. Micturition in the unanesthetizedrat spinal vs. peripheral pharmacology of the adrenergicsystem. J Pharmacol Exp Ther 1988 : 426 ~ 35
/ 1997 / Influence of prostatesize on terazosin efficacy 4 : 358 ~ 361
/ / Kontturi MJ. Urodynamic effects of finasteridein the treatment of bladder outlet obstruction due to benignprostatic hyperplasia. J Urol 1993 : 342 ~ 4
/ / The response to alpha blockadein benign prostatic hyperplasia is related to the percentarea density of prostate smooth muscle : 297 ~ 307
/ / Yaksh TL. Micturition in the unanesthetizedrat spinal vs. peripheral pharmacology of the adrenergicsystem. J Pharmacol Exp Ther 1988 : 426 ~ 35
/ 1997 / Influence of prostatesize on terazosin efficacy 4 : 358 ~ 361
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