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자료유형
학술저널
저자정보
저널정보
조선대학교 치의학연구원 Oral Biology Research Oral Biology Research 제40권 제3호
발행연도
2016.1
수록면
117 - 123 (7page)

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Tantalum (Ta) coating is expected to improve clinical outcomes of titanium (Ti) dental implants due to its anticorrosion and biocompatibility. The purpose of this study was to evaluate the effect of Ta coating on surface characteristics and osteoblastic cell response of Ti-6Al-4V alloy surface. Radio frequency (RF) magnetron sputtering method was used to develop the Ta coating layer on Ti- 6Al-4V disks. Surface properties were analyzed by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Electrochemical test was performed to evaluate the corrosion behavior. Cell responses were evaluated using 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (MTT) assay and alkaline phosphatase (ALP) activity. Ta coating layer was formed with a uniform thickness. In electrochemical test, the passive layer was more uniform and stable in Ta-coating group than Ti-6Al-4V group. Cell morphology showed no difference between Ti-6Al-4V group and Ta-coating group. Ta-coating group showed higher cell proliferation than Ti-6Al-4V group at 1, 3 and 5 days (p<0.05). There was no significant difference in ALP activity level between two groups (p>0.05). These results suggest that Ta coating on Ti-6Al-4V alloy could enhance surface properties and early osteogenic responses.

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