갑상선 양성 종양으로 갑상선 부분절제술을 시행한 환자에서 수술 전후 갑상선 기능의 변화

김정한; 황윤선; 배수연; 조동희; 최민영; 최준호; 이정언; 김지수; 남석진; 양정현

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자료유형: 학술저널

저자정보: 김정한 황윤선 배수연 조동희 최민영 최준호 이정언 김지수 남석진 양정현

저널정보: 대한갑상선-내분비외과학회 The Journal of Endocrine Surgery The Journal of Endocrine Surgery 제10권 제4호

발행연도: 2010.1

수록면: 213 - 219 (7page)

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이 논문의 연구 히스토리 (2)

2010

갑상선 양성 종양으로 갑상선 부분절제술을 시행한 환자에서 수술 전후 갑상선 기능의 변화

김정한 , 황윤선 , 배수연 외 7명 The Journal of Endocrine Surgery 2010.01 학술저널

2004

Graves’ Disease 환자에서의 갑상선아전절제술

김정한 , 김대겸 , 우상욱 외 2명 대한외과학회 학술대회 초록집 2004.10 학술대회자료

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Purpose: Lobectomy or subtotal thyroidectomy in patients with a benign thyroid tumor or goiter can give rise to hypothyroidism due to the reduced volume of the hormone-secreting thyroid gland. This study investigated the incidence of hypothyroidism in such patients and the clinical risk factors. Methods: One hundred seven patients who underwent partial thyroidectomy for benign thyroid tumor or goiter from January 2003 to February 2005 in our institution were reviewed retrospectively. Patients who had been preoperatively diagnosed with hyper- or hypothyroidism preoperatively were excluded. Postoperative hypothyroidism was defined as an elevated serum thyroid stimulating hormone (TSH) level ＞6.5μIU/L at about 6 months post- thyroidectomy. 책임저자 : 김정한, 서울시 강남구 일원동 50번지󰂕135-710, 삼성서울병원 외과Tel: 02-3410-0286, Fax: 02-3410-6982E-mail: jhkim15@skku.edu 접수일：2010년 10월 11일, 게재승인일：2010년 10월 20일Results: The mean age of the 107 patients was 42.2 years. Ninety patients (84.1%) were female. Subtotal thyroidectomy was performed in 20 patients, lobectomy in 83 patients and enucleation in four patients. The most common pathologic diagnosis was nodular hyperplasia (86.0%). Postoperative hypothyroidism developed after surgery in 19 (21.8%) patients. Patients were evaluated for age, gender, preoperative TSH level, tumor size, tumor number, extent of the resection, thickness of thyroid isthmus and the presence of pathologic thyroiditis or thyroid autoantibody. Advanced age, elevated preoperative TSH level and extensive resection of the thyroid gland were significantly associated with postoperative hypothyroidism. Conclusion: Since many patients with a benign thyroid nodule can maintain a normal thyroid function even after thyroidectomy, preservation of more thyroid tissue during the operation is desirable, especially in young patients with a low-normal TSH level, unless the possibility of disease recurrence is high. (Korean J Endocrine Surg 2010;10:213- 219)

#갑상선 양성 종양 #갑상선 절제술 #갑상선 기능저하증 #Benign thyroid nodule #Thyroidectomy #Hypothyroidism

참고문헌 (23)

참고문헌 신청

Bakiri F / 2006 / Subtotal thyroidectomy for benign multinodular goiter: a 6-month postoperative study of the remnant's function and sonographic aspect / World J Surg 30 : 1

Basili G / 2003 / Risk of recurrence following partial thyroidectomy for benign lesions. Report of 58 patients 15∼25 years after surgery / Minerva Chir 58 : 321 ~ 329

Bauer DC / 2001 / Risk for fracture in women with low serum levels of thyroid-stimulating hormone / Ann Intern Med 134 : 561 ~ 568

Bellantone R / 2004 / Predictive factors for recurrence after thyroid lobectomy for unilateral non-toxic goiter in an endemic area: results of a multivariate analysis / Surg

Berglund J / 1990 / Indications for thyroxine therapy after surgery for nontoxic benign goitre / Acta Chir Scand 156 : 433 ~ 438

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