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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 10 - 14 (5page)
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Purpose: Thyroidectomy without prophylactic central neck dissection may be recom-mended for small (T1 or T2) papillary thyroid carcinoma (PTC). The aim of this study was to determine the incidence and predictive factors of central cervical lymph node metastasis in T1/2 papillary thyroid carcinoma.Methods: A retrospective review of 877 patients with T1/2 PTC who underwent thyroidectomy and central lymph node dissection with or without lateral lymph node dissection from March 2007 to February 2014 was performed. The clinicopathologic results were reviewed and the incidence and predictive factors of central cervical lymph node metastasis (LNM) were analyzed.Results: The overall frequency of central LNM was 29.8%. In univariate analysis, male, younger age, bilaterality, multifocality, larger tumor size, lymphovascular invasion, and lateral lymph node metastasis were associated with central LNM. In multivariate analysis, younger age, larger tumor size, lymphovascular invasion, and lateral lymph node metastasis were independent variables of central LNM.Conclusion: Central LNM is associated with younger age, larger tumor, lymphovascular invasion, and lateral lymph node metastasis in small (T1/2) PTC patients. Prophylactic central lymph node dissection should be considered in patients with risk factors.
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참고문헌 (21)
참고문헌 신청
Carty SE / 2009 / Consensus statement on the terminology and classification of central neck dissection for thyroid cancer / Thyroid 19 : 1153 ~ 1158
Chen AY / 2009 / Increasing incidence of differentiated thyroid cancer in the United States, 1988-2005 / Cancer 115 : 3801 ~ 3807
Chow SM / 2003 / Papillary microcarcinoma of the thyroid-Prognostic significance of lymph node metastasis and multifocality / Cancer 98 : 31 ~ 40
Cooper DS / 2009 / Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 19 : 1167 ~ 1214
Gimm O / 1998 / Pattern of lymph node metastases in papillary thyroid carcinoma / Br J Surg 85 : 252 ~ 254
Chen AY / 2009 / Increasing incidence of differentiated thyroid cancer in the United States, 1988-2005 / Cancer 115 : 3801 ~ 3807
Chow SM / 2003 / Papillary microcarcinoma of the thyroid-Prognostic significance of lymph node metastasis and multifocality / Cancer 98 : 31 ~ 40
Cooper DS / 2009 / Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 19 : 1167 ~ 1214
Gimm O / 1998 / Pattern of lymph node metastases in papillary thyroid carcinoma / Br J Surg 85 : 252 ~ 254
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