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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 36 - 41 (6page)
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Background and Objectives: Thyroid dysfunction during pregnancy can result in many complications for both mother and infant. Due to the physiologic changes in thyroid stimulating hormone (TSH) level during early pregnancy, it is recommend to use trimester-specific reference ranges for every population. We obtained the reference range of TSH during the first trimester in Korean women according to gestational week. Materials and Methods: The study population consisted of pregnant women who had undergone a TSH screening during the first trimester of pregnancy (n=8365) and nonpregnant women (n=1835). Results: Median concentration of serum TSH decreased significantly from the 5th to 8th week of gestation (median TSH concentration: 2.00 mIU/L for 5 weeks; 1.70 mIU/L for 6 weeks; 1.40 mIU/L for 7 weeks; 1.05 mIU/L for 8 weeks). However, there was no significant difference in median concentration of serum TSH from the 8th to 12th weeks of gestation. Using the fixed cut-off value of TSH ＞3.66 mIU/L, the diagnosis rate of subclinical hypothyroidism was 15.0% for 5 weeks, 10.0% for 6 weeks, 5.9% for 7 weeks, and 3.6% for 8-12 weeks. Conclusion: When interpreting the TSH test for pregnancy (maternal thyroid function), we should consider that the TSH level decreases significantly during the early first trimester.
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등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Alexander EK / 2017 / Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum / Thyroid 27 (3)
Ballabio M / 1991 / Pregnancy-induced changes in thyroid function: role of human chorionic gonadotropin as putative regulator of maternal thyroid / J Clin Endocrinol Metab 7
Blatt AJ / 2012 / National status of testing for hypothyroidism during pregnancy and postpartum / J Clin Endocrinol Metab 97 (3) : 777 ~ 784
Bryant SN / 2015 / An an
Casey BM / 2005 / Subclinical hypothyroidism and pregnancy outcomes / Obstet Gynecol 105 (2) : 239 ~ 245
Ballabio M / 1991 / Pregnancy-induced changes in thyroid function: role of human chorionic gonadotropin as putative regulator of maternal thyroid / J Clin Endocrinol Metab 7
Blatt AJ / 2012 / National status of testing for hypothyroidism during pregnancy and postpartum / J Clin Endocrinol Metab 97 (3) : 777 ~ 784
Bryant SN / 2015 / An an
Casey BM / 2005 / Subclinical hypothyroidism and pregnancy outcomes / Obstet Gynecol 105 (2) : 239 ~ 245
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