지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.1
- 수록면
- 385 - 394 (10page)
이용수
초록· 키워드
오류제보하기
Leptin receptor deficiency causes morbid obesity and hyperlipidemia in mice. Since physical exercise enhances energy expenditure, it is an important part of successful weight-control regimens. We investi-gated the mechanism by which swim training regulates leptin receptor deficiency-induced obesity and lipid disorder in a mou se model of obesity (obese db/db mouse). Swim training for 6 weeks significantly decreased body weight gain and adipose tissue mass in both sexes of obese and lean mice, compared to their respective sedentary controls. These effects were particularly evident in obese mice. Swim training also caused significant decreases in serum cholesterol in both obese and lean mice. In obese mice, swim training increased the levels of mRNAs and proteins encoding unc oupling protein 1 (UCP1), UCP2 and UCP3 in brown adipose tissue, white adipose tissue and skeletal muscle, respectively. In conclusion, these findings suggest that, in mice, swim training can effectively prevent body weight gain, adiposity and lipid di sorders caused by leptin receptor deficiency, in part through activation of UCPs in adipose tissue and skeletal muscle, which may contribute to alleviating metabolic syndromes, such as obesity, hyperlipid emia and type 2 diabetes.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Arner P / jclininvest1990;85 / Adrenergic regulation of lipolysis in situ at rest and during exercise : 893 ~ 8
Baar K / 2004 / Involvement of PPAR gamma co-activator-1, nuclear respiratory factors 1 and 2, and PPAR alpha in the adaptive response to endurance exercise 63 : 269 ~ 273
Boden G / 1997 / Role of fatty acids in the pathogenesis of insulin resistance and NIDDM 46 : 3 ~ 10
Brook GA / 1995 / Human bioenergetics and its applications 2 : 151 ~ 158
Buemann B / 1996 / Effects of exercise training on abdominal obesity and related metabolic complications 21 : 191 ~ 212
Baar K / 2004 / Involvement of PPAR gamma co-activator-1, nuclear respiratory factors 1 and 2, and PPAR alpha in the adaptive response to endurance exercise 63 : 269 ~ 273
Boden G / 1997 / Role of fatty acids in the pathogenesis of insulin resistance and NIDDM 46 : 3 ~ 10
Brook GA / 1995 / Human bioenergetics and its applications 2 : 151 ~ 158
Buemann B / 1996 / Effects of exercise training on abdominal obesity and related metabolic complications 21 : 191 ~ 212
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Dysregulation of Cannabinoid CB1 Receptor Expression in Subcutaneous Adipocytes of Obese Individuals
Animal cells and systems
2009 .01
-
The macrophage migration inhibitory factor protein superfamily in obesity and wound repair
Experimental and Molecular Medicine
2015 .01
-
Adipose sirtuin 6 drives macrophage polarization toward M2 through IL-4 production and maintains systemic insulin sensitivity in mice and humans
Experimental and Molecular Medicine
2019 .01
-
Different Water temperature and Swim Training on Tuberculosis infection of trained mice
한국생명과학회 심포지움
2005 .09
-
Fenofibrate inhibits adipocyte hypertrophy and insulin resistance by activating adipose PPARα in high fat diet-induced obese mice
Experimental and Molecular Medicine
2009 .01
-
Vitamin D regulation of adipogenesis and adipose tissue functions
Nutrition Research and Practice
2020 .12
-
Vitamin D regulation of adipogenesis and adipose tissue functions
Nutrition Research and Practice
2020 .12
-
Inflammation in Obesity
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2016 .12
-
Assessment of The Accuracy of The MR Abdominal Adipose Tissue Volumetry using 3D Gradient Dual Echo 2-Point DIXON Technique using CT as Reference
Journal of Magnetics
2016 .12
-
BAFF knockout improves systemic inflammation via regulating adipose tissue istribution in high-fat diet-induced obesity
Experimental and Molecular Medicine
2015 .01
-
비만과 대사증후군 동반 여부에 따른 한국 성인 여성의 영양소 섭취 상태 평가
대한지역사회영양학회지
2010 .10
-
Obesity Regulation through Gut Microbiota Modulation and Adipose Tissue Browning
생명과학회지
2019 .08
-
Heterogeneity of white adipose tissue: molecular basis and clinical implications
Experimental and Molecular Medicine
2016 .01
-
Time-Dependent Hepatic Proteome Analysis in Lean and Diet-Induced Obese Mice
Journal of Microbiology and Biotechnology
2011 .01
-
A Study on Weight Control Program for 4th and 5th Grade Obese Children in Elementary School
Nutritional Sciences
1998 .11
-
Anti-Obesity Effects of a Mixture of Fermented Ginseng, Bifidobacterium longum BORI, and Lactobacillus paracasei CH88 in High-Fat Diet-Fed Mice
Journal of Microbiology and Biotechnology
2018 .01
-
Anti-obesity effects of hot water extract from Wasabi (Wasabia japonica Matsum.) leaves in mice fed high-fat diets
Nutrition Research and Practice
2013 .08
-
Anti-obesity effects of hot water extract from Wasabi (Wasabia japonica Matsum.) leaves in mice fed high-fat diets
Nutrition Research and Practice
2013 .08
-
Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning
Experimental and Molecular Medicine
2019 .01
-
비만정도에 따른 우울 및 스트레스 : 정상체중, 비만, 고도비만 집단의 비교
한국생활과학회지
2012 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0