지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 289 - 292 (4page)
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초록· 키워드
오류제보하기
Objectives: Chronic periodontitis is a common inflammatory disease of the oral cavity that causes destruction of periodontal tissues and bone around the teeth. Sclerostin is a protein encoded by the SOST gene. In this study, gingival crevicular fluid (GCF) levels of sclerostin in patients with chronic periodontitis were compared with those of healthy subjects.Materials and Methods: In this case-control study, a total of 40 subjects were enrolled and divided into the healthy group (n=23) and chronic peri-odontitis group (n=17). GCF samples were collected, and the concentration of sclerostin was evaluated using enzyme-linked immunosorbent assay. Comparison of significance between groups was assessed using Mann-Whitney U test.Results: Sclerostin concentration was significantly higher in the chronic periodontitis group compared with the healthy group (P<0.005). Conclusion: Despite the limitations of this study, sclerostin can be a possible marker for assessment of periodontal health status.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Kornman KS / 1997 / The host response to the microbial challenge in periodontitis: assembling the players / Periodontol 2000 14:33~53
Bascones-Martínez A / 2009 / Host defence mechanisms against bacterial aggression in periodontal disease: basic mechanisms / Med Oral Patol Oral Cir Bucal 14:e680~e685
Kumar PS / 2003 / New bacterial species associated with chronic periodontitis / J Dent Res 82:338~344
Buduneli N / 2011 / Host-derived diagnostic markers related to soft tissue destruction and bone degradation in periodontitis / J Clin Periodontol 38(Suppl 11):85~105
Champagne CM / 2003 / Potential for gingival crevice fluid measures as predictors of risk for periodontal diseases / Periodontol 2000 31:167~180
Bascones-Martínez A / 2009 / Host defence mechanisms against bacterial aggression in periodontal disease: basic mechanisms / Med Oral Patol Oral Cir Bucal 14:e680~e685
Kumar PS / 2003 / New bacterial species associated with chronic periodontitis / J Dent Res 82:338~344
Buduneli N / 2011 / Host-derived diagnostic markers related to soft tissue destruction and bone degradation in periodontitis / J Clin Periodontol 38(Suppl 11):85~105
Champagne CM / 2003 / Potential for gingival crevice fluid measures as predictors of risk for periodontal diseases / Periodontol 2000 31:167~180
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