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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 183 - 186 (4page)
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초록· 키워드
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Purpose: To evaluate the protective effects of epigallocatechin gallate (EGCG) against UV irradiation of cultured human lens epithelial cells.
Methods: We irradiated cultured human lens epithelial cells with a 30-second pulse from a UV lamp with an irradiance of 0.6 mW/cm2. Five minutes and 1 hour after UV irradiation, we administered 0, 5, 10, 15, 25, 50, or 100 uM EGCG. The cell number was measured with a microscopic counting chamber and cell viability was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay.
Results: Compared to untreated cells, the total number of cultured human lens epithelial cells was markedly higher after UV irradiation. In a dose-dependent manner, viability was also higher in EGCG-treated cells.
Conclusions: EGCG increased the cell count and cell viability after UV irradiation of cultured human lens epithelial cells, indicating that EGCG can protect lens epithelium against UV damage.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Bettuzzi S / 2006 / Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia:
Buttemeyer R / 2003 / Epigallocatechin gallate can significantly decrease free oxygen radicals in the reperfusion injury in vivo / Transplant Proc 35 : 3116 ~ 20
Demeule M / 2002 / Green tea catechins as novel antitumor and antiangiogenic compounds / Curr Med Chem Anticancer Agents 2 : 441 ~ 63
Mandel S / 2004 / Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative disea
Margrain TH / 2004 / Do blue light filters confer protection against age-related macular degeneration / Prog Retin Eye Res 23 : 523 ~ 31
Buttemeyer R / 2003 / Epigallocatechin gallate can significantly decrease free oxygen radicals in the reperfusion injury in vivo / Transplant Proc 35 : 3116 ~ 20
Demeule M / 2002 / Green tea catechins as novel antitumor and antiangiogenic compounds / Curr Med Chem Anticancer Agents 2 : 441 ~ 63
Mandel S / 2004 / Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative disea
Margrain TH / 2004 / Do blue light filters confer protection against age-related macular degeneration / Prog Retin Eye Res 23 : 523 ~ 31
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Protective Effects of Epigallocatechin Gallate after UV Irradiation in Cultured Human Retinal Pigment Epithelial Cells
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Activity of Green Tea Polyphenol Epigallocatechin-3-gallate Against Ovarian Carcinoma Cell Lines
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(-)-Epigallocatechin-3-Gallate Induces Apoptosis and Inhibits Invasion and Migration of Human Cervical Cancer Cells
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Epigallocatechin Gallate, a Constituent of Green Tea, Regulates High Glucose-induced Apoptosis
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EGCG prevents benzene-induced apotosis in lung epithelial cells
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Protective Effects of Verapamil against H<sub>2</sub>O<sub>2</sub>-Induced Apoptosis in Human Lens Epithelial Cells
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마우스세포주 Balb/c 3T3 A31-1-1에서 Epigallocatechin gallate(EGCG)의 세포암화 억제효과에 대한 유전자발현 해석
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2006 .12
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Epigallocatechin-3-gallate Regulates Inducible Nitric Oxide Synthase Expression in Human Umbilical Vein Endothelial Cells
Laboratory Animal Research
2011 .06
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Inhibition of Proliferation and Induction of Apoptosis by EGCG in Human Osteogenic Sarcoma (HOS) Cells
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Epigallocatechine gallate에 의한 amyloid β peptide 유도성 신경세포독성의 억제
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2005 .06
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The Protective Effect of Epigallocatechin-3 Gallate on Ischemia/ Reperfusion Injury in Isolated Rat Hearts: An ex vivo Approach
The Korean Journal of Physiology & Pharmacology
2011 .01
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Effect of Heat-epimerized-catechin-mixture Rich in Gallocatechin-3-gallate on Skin Barrier Recovery
대한화장품학회지
2008 .01
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Effect of Epigallocatechin-3-Gallate on PMA-Induced MUC5B Expression in Human Airway Epithelial Cells
Clinical and Experimental Otorhinolaryngology
2013 .01
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난소암 세포주에서 녹차 추출물의 항암 작용
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