지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a disease that is characterized by acute psychiatric symptoms, seizures, and central hypoventilation. Patients with anti-NMDAR encephalitis exhibit speech alterations, insomnia, seizures, and movement disorders. We describe a previously healthy 6-year-old girl who presented with seizures, disorientation, and fever. Over the five weeks of treatment, the patient exhibited progressive neurologic symptoms, including a change in mental status. Her serum and cerebrospinal fluid contained high titers of antibodies against the NMDAR, and she was diagnosed with anti-NMDAR encephalitis. She was treated with plasmapheresis, steroid pulse therapy, intravenous immunoglobulins, and repeated doses of rituximab. After the patient was diagnosed with a concomitant ovarian teratoma, a unilateral salpingo-oophorectomy was performed. A histopathologic examination revealed that neuronal elements accounted for 60% of the resected ovarian teratoma. The patient’s clinical symptoms and antibody titers improved after the surgical treatment and rituximab therapy. These observations suggested that patients with high titers of anti-NMDAR antibodies should be examined for the presence and quantity of neuronal components in concurrent ovarian teratomas.
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등록된 정보가 없습니다.
참고문헌 (9)
참고문헌 신청
Armangue T / 2012 / Autoimmune Encephalitis in Children / J Child Neurol 27 : 1460 ~ 1469
Dalmau J / 2007 / Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma / Ann Neurol 61 : 25 ~ 36
Dalmau J / 2008 / Anti-NMDA-receptor encephalitis : case series and analysis of the effects of antibodies / Lancet Neurol 2008; 7 : 1091 ~ 1098
Dalmau J / 2011 / Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis / Lancet Neurol 10 : 63 ~ 74
Day GS / 2014 / Abnormal neurons in teratomas in NMDAR encephalitis / JAMA Neurol 71 : 717 ~ 724
Dalmau J / 2007 / Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma / Ann Neurol 61 : 25 ~ 36
Dalmau J / 2008 / Anti-NMDA-receptor encephalitis : case series and analysis of the effects of antibodies / Lancet Neurol 2008; 7 : 1091 ~ 1098
Dalmau J / 2011 / Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis / Lancet Neurol 10 : 63 ~ 74
Day GS / 2014 / Abnormal neurons in teratomas in NMDAR encephalitis / JAMA Neurol 71 : 717 ~ 724
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Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis Associated With Mediastinal and Ovarian Teratomas: A Case Report
Journal of Korean Medical Science
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이상행동으로 내원한 난소 기형종 관련 항NMDA 수용체 뇌염
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Anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma in Korea: three case reports
Journal of Yeungnam Medical Science
2021 .10
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Anti-N-methyl-D-aspartate Receptor Encephalitis: a Rare Complication of Ovarian Teratoma
Journal of Korean Medical Science
2020 .01
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Case of anti-N-methyl D-aspartate receptor encephalitis associated with ovarian teratoma presenting as suicidal ideation
대한응급의학회지
2024 .04
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조현병의 증상으로 발현한 신생물딸림변연뇌염 1예
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Thyroid Autoantibody Positive Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Dementia and Neurocognitive Disorders(대한치매학회지)
2016 .01
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Fever of Unknown Origin: An Unusual Presentation of Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Infection and Chemotherapy
2015 .01
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Anesthesia for ovarian teratoma resection using remimazolam and remifentanil in a patient with anti-N-methyl-D-aspartate receptor encephalitis -two case reports-
Korean Journal of Anesthesiology
2022 .12
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Occult Growing Teratoma as the Cause of Protracted Symptoms in a Patient with Anti-NMDA-Receptor Encephalitis and Prior Ovarian Teratoma Removal: Implications for Continued Monitoring and Treatment
Journal of Clinical Neurology
2021 .01
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Childhood Onset of Anti-N-Methyl-D-Aspartate Receptor Encephalitis Without Teratoma Masquerading as a Psychotic Disorder
소아청소년정신의학
2019 .07
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Identification of Medium-Length Antineurofilament Autoantibodies in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Journal of Clinical Neurology
2020 .01
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항-NMDA-수용체 뇌염으로 진단된 긴장증 사례
대한조현병학회지
2017 .04
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Factors Affecting the Response to First-Line Treatments in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Journal of Clinical Neurology
2019 .01
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Anti-N-methyl-D-aspartate Receptor Encephalitis in a Patient with Thyroid Eye Disease
Korean Journal of Ophthalmology
2019 .01
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Anti-N-Methyl-D-Aspartate Receptor Encephalitis Presenting Progressive Dyslexia: A Case Report
Dementia and Neurocognitive Disorders(대한치매학회지)
2015 .01
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전경부에 발생한 성숙 기형종 증례
임상이비인후과
2020 .01
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Analysis of Risk Factors for a Poor Prognosis in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis and Construction of a Prognostic Composite Score
Journal of Clinical Neurology
2020 .01
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A Case of Anti-NMDA Receptor Encephalitis with Normal Findings on Initial Diagnostic Tests
Dementia and Neurocognitive Disorders(대한치매학회지)
2020 .01
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Anti-N-Methyl-D-Aspartate Receptor Encephalitis in a Patient with Systemic Lupus Erythematosus
Journal of Clinical Neurology
2016 .01
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