지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 121 - 127 (7page)
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초록· 키워드
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The incidence of cerebral palsy has not decreased despite advances in neonatal care. Preterm infants are at a high risk of cerebral palsy. Moreover, preterm infants might experience permanent neurological sequelae due to injury in the preterm brain. Although the etiology of preterm brain injury is not fully understood, preterm brain injury is strongly associated with abnormal cerebral perfusion and oxygenation. Monitoring systemic blood pressure or arterial oxygen saturation using pulse oximetry is not enough to guarantee proper cerebral perfusion or oxygenation. Early detection of improper cerebral perfusion can prevent irreversible cerebral damage. To decrease brain injury through the early detection of under-perfusion and deoxygenation, other diagnostic modalities are needed. Near-infrared spectroscopy can continuously and noninvasively monitor regional oxygen saturation (rSO2), which reflects the perfusion and oxygenation status of tissues at bedside. Near-infrared spectroscopy represents a balance between tissue oxygen supply and demand. Cerebral rSO2 monitoring has been used most frequently in neonatal cardiac surgery to monitor cerebral oxygenation and prevent hypoxic damage or shock. Recently, cerebral, renal, or splanchnic rSO2 in neonates is frequently monitored. The progression of a disease, brain injury, and death can be prevented by detecting changes in rSO2 values using near-infrared spectroscopy. In this article, the basic principles, usefulness, and applications of near-infrared spectroscopy in neonates are discussed.
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등록된 정보가 없습니다.
참고문헌 (43)
참고문헌 신청
Novak I / 2017 / Early, accurate diagnosis and early intervention in cerebral palsy: advances in diagnosis and treatment / JAMA Pediatr 171:897~907
Babcock MA / 2009 / Injury to the preterm brain and cerebral palsy: clinical aspects, molecular mechanisms, unanswered questions, and future research directions / J Child Neurol 24:1064~1084
Van Bel F / 1987 / Aetiological role of cerebral blood-flow alterations in development and extension of peri-intraventricular haemorrhage / Dev Med Child Neurol 29:601~614
Verhagen EA / 2015 / Cerebral oxygenation is associated with neurodevelopmental outcome of preterm children at age 2to 3 years / Dev Med Child Neurol 57:449~455
Børch K / 2010 / Cerebral white matter blood flow and arterial blood pressure in preterm infants / Acta Paediatr 99:1489~1492
Babcock MA / 2009 / Injury to the preterm brain and cerebral palsy: clinical aspects, molecular mechanisms, unanswered questions, and future research directions / J Child Neurol 24:1064~1084
Van Bel F / 1987 / Aetiological role of cerebral blood-flow alterations in development and extension of peri-intraventricular haemorrhage / Dev Med Child Neurol 29:601~614
Verhagen EA / 2015 / Cerebral oxygenation is associated with neurodevelopmental outcome of preterm children at age 2to 3 years / Dev Med Child Neurol 57:449~455
Børch K / 2010 / Cerebral white matter blood flow and arterial blood pressure in preterm infants / Acta Paediatr 99:1489~1492
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