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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 162 - 172 (11page)
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초록· 키워드
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Aspirin has been used for decades for the primary and secondary prevention of cardiovascular disease (CVD). The effect of aspirin in secondary prevention is well-known but is still debatable for primary prevention. Despite the controversy, aspirin is believed to have a beneficial effect in primary prevention and has been widely used. However, whether the doubts concerning the wide use of aspirin are correct has resulted in the publication of data from several large clinical trials recently. There are several clinical guidelines from various international organizations on the use of aspirin for the primary prevention of CVD, and they offer some conflicting recommendations. A reduction in the overall incidence of CVD with the development of modern prevention therapies has weakened the impact of aspirin in primary prevention. Large randomized clinical trials have found decreased or no difference in CVD events but a significant increase in the risk of bleeding. Taking aspirin for the primary prevention of CVD is no longer recommended, especially for patients who have a low to moderate risk. An assessment of the balance between the benefits and risks of aspirin use should be considered.
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참고문헌 (50)
참고문헌 신청
Yusuf S / 2001 / Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization / Circulation 104:2746~2753
Yusuf S / 2001 / Global burden of cardiovascular diseases: Part II: variations in cardiovascular disease by specific ethnic groups and geographic regions and prevention strategies / Circulation 104:2855~2864
Dalen JE / 2014 / The epidemic of the 20th century: coronary heart disease / Am J Med 127:807~812
Hennekens CH / 1997 / Aspirin as a therapeutic agent in cardiovascular disease: a statement for healthcare professionals from the American Heart Association / Circulation 96:2751~2753
Baigent C / 2009 / Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials / Lancet 373:1849~1860
Yusuf S / 2001 / Global burden of cardiovascular diseases: Part II: variations in cardiovascular disease by specific ethnic groups and geographic regions and prevention strategies / Circulation 104:2855~2864
Dalen JE / 2014 / The epidemic of the 20th century: coronary heart disease / Am J Med 127:807~812
Hennekens CH / 1997 / Aspirin as a therapeutic agent in cardiovascular disease: a statement for healthcare professionals from the American Heart Association / Circulation 96:2751~2753
Baigent C / 2009 / Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials / Lancet 373:1849~1860
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