지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 5 - 12 (8page)
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초록· 키워드
오류제보하기
Prostate cancer (CaP) is the most common cancer diagnosed among men in the United States and the fifth most common cancer among men in Korea. Unfortunately, the early stages of CaP may have no symptoms. Thus, early detection is very important and physicians managing voiding dysfunction must have awareness about CaP. The traditional tests used for early detection of CaP are the prostate-specific antigen (PSA) blood test and digital rectal examination. However, a high PSA level is not specific for CaP. Benign prostatic hyperplasia, prostatitis, urinary tract infection, and urinary retention can all cause a high PSA level. Thus, no test shows sufficient accuracy to truly be useful for screening men for CaP. A prostate biopsy is the only method that yields a definitive diagnosis of CaP; however, this test is invasive and uncomfortable. Recently, new biomarkers for CaP detection have been proposed to improve the accuracy of the PSA test. In this review, we summarize our knowledge of various new biomarkers, including PSA-associated biomarkers (the prostate health index and 4Kscore), molecular biomarkers (PCA3, TMPRSS2: ERG fusion gene, and various miRNAs), and proteomics-associated biomarkers, and the ways in which they may improve the detection rate of CaP. Accordingly, this review can raise awareness about CaP to physicians managing voiding dysfunction and be a good reference for them.
목차
등록된 정보가 없습니다.
참고문헌 (51)
참고문헌 신청
Siegel RL / 2018 / Cancer statistics, 2018 / CA Cancer J Clin 68:7~30
정규원 / 2018 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2015 / Cancer Research and Treatment 50(2):303~316
송완 / 2015 / Incidence of kidney, bladder, and prostate cancers in Korea: An update / Investigative and Clinical Urology 56(6):422~428
Obirieze AC / 2015 / African-American men with low-risk prostate cancer : modern treatment and outcome trends / J Racial Ethn Health Disparities 2:295~302
Gann PH / 1995 / A prospective evaluation of plasma prostate-specific antigen for detection of prostatic cancer / JAMA 273:289~294
정규원 / 2018 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2015 / Cancer Research and Treatment 50(2):303~316
송완 / 2015 / Incidence of kidney, bladder, and prostate cancers in Korea: An update / Investigative and Clinical Urology 56(6):422~428
Obirieze AC / 2015 / African-American men with low-risk prostate cancer : modern treatment and outcome trends / J Racial Ethn Health Disparities 2:295~302
Gann PH / 1995 / A prospective evaluation of plasma prostate-specific antigen for detection of prostatic cancer / JAMA 273:289~294
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