지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국약제학회 Journal of Pharmaceutical Investigation Journal of Pharmaceutical Investigation 제49권 제4호
- 발행연도
- 2019.1
- 수록면
- 337 - 346 (10page)
이용수
초록· 키워드
오류제보하기
Background Poly(glycolic acid), poly(lactic acid) and poly(lactic-co-glycolic acid) were approved by the United States Food and Drug Administration (FDA) in the 1970s as materials for the manufacturing of bioresorbable surgical sutures, but soon became the reference materials for the preparation of sustained release formulations, especially injectable microparticles. Since the 1986 approval of Decapeptyl ® SR, the first product based on PLGA microspheres, more than 15 such products have been approved for clinical use. Area covered This article highlights the key steps that brought to the development of injectable poly(lactic acid)/poly(lacticco- glycolic acid) microparticles for the sustained release of active pharmaceutical ingredients. After a brief history of some pioneering works that opened the field of controlled drug delivery, the key steps that led to the development of these polymers and the approval of the first microparticle-based medicinal products are reviewed. Finally, the general characteristics of these polymers are described and the classical preparation method is explained. Expert opinion Poly(lactic acid)/poly(lactic-co-glycolic acid) microparticles are among the most successful drug delivery systems. The recent approval of new medicinal products based on PLGA microspheres is the proof that pharmaceutical companies have continued to exploit this drug delivery technology. The possible development of generics and the continuous discovery of therapeutic peptides will hopefully further the success of microsphere technology.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Biocompatibility, biodegradation and biomedical applications of poly(lactic acid)/poly(lactic‑co‑glycolic acid) micro and nanoparticles
Journal of Pharmaceutical Investigation
2019 .01
-
Poly(lactic acid)/poly(lactic‑co‑glycolic acid) particulate carriers for pulmonary drug delivery
Journal of Pharmaceutical Investigation
2019 .01
-
약물지연방출을 위한 스테레오컴플렉스 PLA 원반형 마이크로입자
의공학회지
2020 .01
-
Poly lactic-co glycolic acid (PLGA) Nanofibrous Scaffold Chemically Coated with Gold-nanoparticles (GNPs) as Osteoinductive Agent for Osteogenesis
대한치과재료학회 학술대회
2016 .11
-
Poly-L-Lactic Acid Increases Collagen Gene Expression and Synthesis in Cultured Dermal Fibroblast (Hs68) Through the p38 MAPK Pathway
Annals of Dermatology
2019 .01
-
Controlled release and targeted drug delivery with poly(lactic-co-glycolic acid) nanoparticles: reviewing two decades of research
Journal of Pharmaceutical Investigation
2022 .11
-
Late-Onset Methicillin-Resistant Staphylococcus aureus Infection after Facial Poly-L-Lactic Acid Injection
Archives of plastic surgery : APS
2017 .01
-
Hollow Poly(lactic acid) and Poly(lactic acid)/polyethylene glycol Microspheres Prepared by A Simple Fluidic Device
의공학회지
2021 .01
-
Management of a Visible Nodule Following Poly-L-Lactic Acid Injection in the Periorbital Area
Archives of Aesthetic Plastic Surgery
2016 .01
-
Recent advances in polymeric drug delivery systems
생체재료학회지
2020 .01
-
Late Onset Foreign Body Reaction due to Poly-L-Lactic Acid Facial Injections for Cosmetic Purpose
Annals of Dermatology
2020 .01
-
Treatment of an Atrophic Scar with Fractional Carbon Dioxide Laser-assisted Poly-L-lactic Acid Delivery
MEDICAL LASERS
2021 .09
-
PEGylated polylactide (PLA) and poly (lactic‑co‑glycolic acid) (PLGA) copolymers for the design of drug delivery systems
Journal of Pharmaceutical Investigation
2019 .01
-
Effect of lactic acid bacteria on the pharmacokinetics and metabolism of ginsenosides in mice
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Lipid-based surface engineering of PLGA nanoparticles for drug and gene delivery applications
생체재료학회지
2016 .12
-
Long acting injectable formulations: the state of the arts and challenges of poly(lactic‑co‑glycolic acid) microsphere, hydrogel, organogel and liquid crystal
Journal of Pharmaceutical Investigation
2019 .01
-
The back-and-forth method: A quick and simple technique for reconstitution of injectable poly-D,L-lactic acid
Archives of Aesthetic Plastic Surgery
2020 .01
-
Meeting the unmet: from traditional to cutting‑edge techniques for poly lactide and poly lactide‑co‑glycolide microparticle manufacturing
Journal of Pharmaceutical Investigation
2019 .01
-
Stromal Lactic Acid Transporters Is Related to High-risk Thyroid Cancer
대한외과학회 학술대회 초록집
2017 .11
-
Preparation of alginate hydrogel microparticles by gelation introducing cross-linkers using droplet-based microfluidics: a review of methods
생체재료학회지
2021 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0