지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 68 - 74 (7page)
이용수
초록· 키워드
오류제보하기
Objectives: Cultivated wild ginseng (cWG), called SanYangSanSam, has been used clinically in patients with chronic fatigue in Korea. Little is known about effects of the ginseng distilled (volatile) components produced during evaporizaiton. Recently, we first identified one major component from cWG distilled extract, panaxydol, by using mass spectrometry. However, functional properties of cWG distilled extract and panaxydol remains elusive. Therefore, the present study evaluated the effect of cWG distilled extract or panaxydol on exercise-induced fatigue in rats. Methods: Fatigue was induced by forced swimming and the immobility time was analyzed in male Sprague-Dawley rats. The animals received intraperitoneally either vehicle, cWG distilled extract, or panaxydol 10 min prior to beginning of the forced swimming test (FST) once daily for 5 days. After the FST on day 5, we also analyzed fatigue-related biochemical levels including blood urea nitrogen (BUN), lactate acid (LAC), and lactate dehydrogenase (LDH) in serum and levels of glycogen in liver and soleus muscle. Results: The forced swimming time in cWG distilled extract (0.6 mL/kg)-treated group was significantly longer than that of control group on day 4 and 5. Panaxydol (0.1 and 0.25 mg/kg)-treated groups showed significantly enhanced performance in the forced swimming, compared to control. In addition, a significant decrease in serum LDH level was found in panaxydol-treated group, while there were no alternations in levels of serum BUN and LAC and glycogen in liver or soleus muscle. Conclusion: The present study demonstrated cWG distilled extract and its active component panaxydol have a function of anti-fatigue.
목차
등록된 정보가 없습니다.
참고문헌 (36)
참고문헌 신청
Tan W / 2012 / Anti-fatigue activity of polysaccharides extract from Radix Rehmanniae Preparata / International journal of biological macromolecules 50(1):59~62
Hao G / 2014 / Effects of intragastric administration of five oyster components on endurance exercise performance in mice / Pharmaceutical biology 52(6):723~728
Shin HJ / 2004 / Enhancement of antitumor effects of paclitaxel(taxol)in combination with red ginseng acidic polysaccharide(RGAP) / Planta medica 70(11):1033~1038
He LX / 2017 / Suppression of TNF-alpha and free radicals reduces systematic inflammatory and metabolic disorders : Radioprotective effects of ginseng oligopeptides on intestinal barrier function and antioxidant defense / The Journal of nutritional biochemistry 40:53~61
Yu Q / 2017 / Ginsenoside Rk1 suppresses pro-inflammatory responses in lipopolysaccharide-stimulated RAW264.7 cells by inhibiting the Jak2/Stat3 pathway / Chinese journal of natural medicines 15(10):751~757
Hao G / 2014 / Effects of intragastric administration of five oyster components on endurance exercise performance in mice / Pharmaceutical biology 52(6):723~728
Shin HJ / 2004 / Enhancement of antitumor effects of paclitaxel(taxol)in combination with red ginseng acidic polysaccharide(RGAP) / Planta medica 70(11):1033~1038
He LX / 2017 / Suppression of TNF-alpha and free radicals reduces systematic inflammatory and metabolic disorders : Radioprotective effects of ginseng oligopeptides on intestinal barrier function and antioxidant defense / The Journal of nutritional biochemistry 40:53~61
Yu Q / 2017 / Ginsenoside Rk1 suppresses pro-inflammatory responses in lipopolysaccharide-stimulated RAW264.7 cells by inhibiting the Jak2/Stat3 pathway / Chinese journal of natural medicines 15(10):751~757
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Elevated Serum Uric Acid in Benign Convulsions with Mild Gastroenteritis in Children
Journal of Clinical Neurology
2019 .01
-
인삼, 산양산삼 및 홍삼 추출물의 항비만 효과
대한한의학방제학회지
2019 .01
-
Clinical Implications of Ketosis in Children with Benign Convulsions with Mild Gastroenteritis
Journal of Clinical Neurology
2020 .01
-
Rh2-enriched Korean Ginseng Ameliorates Chronic Fatigue in a Forced Exercise mouse model
대한한의학회지
2016 .06
-
Fatigue and related factors after liver transplantation
Annals of Hepato-Biliary-Pancreatic Surgery
2015 .11
-
율피증류한약의 피부개선 효과연구
대한한의학회지
2023 .06
-
홍삼 추출물과 아미노산 복합제가 정상 Rat의 지구력 운동에 미치는 영향
대한한방내과학회지
2019 .01
-
Relationship between Changes in Fatigue and Exercise by Follow-Up Period
Korean Journal of Family Medicine
2016 .01
-
Anti-inflammatory effects of porcine placenta in forced swimming tested fatigue mice and RAW264.7 cells
셀메드
2017 .11
-
피로위험관리를 위한 조종사 피로측정방법 고찰
항공우주의학회지
2020 .08
-
Comparison of Fatigue Severity and Quality of Life between Unexplained Fatigue Patients and Explained Fatigue Patients
Korean Journal of Family Medicine
2018 .01
-
경옥고의 항피로 효능
생약학회지(Korean Journal of Pharmacognosy)
2016 .09
-
Standardized Extract (HemoHIM) Ameliorated High Intensity Exercise Induced Fatigue in Mice
Natural Product Sciences
2022 .06
-
A comparative study on immune-stimulatory and antioxidant activities of various types of ginseng extracts in murine and rodent models
Journal of Ginseng Research
2018 .10
-
Impact of fatigue on quality of life among breast cancer patients receiving chemotherapy
Osong Public Health and Research Persptectives
2021 .01
-
Influence of Unilateral Muscle Fatigue in Knee and Ankle Joint on Balance and Gait in Healthy Adults
대한물리치료학회지(JKPT)
2017 .01
-
Cell Proliferation and Antioxidative Effects of Ultrasonic Coffee Extracts
대한의생명과학회지
2017 .12
-
미용사의 지각된 피로도와 건강증진행위에 영향을 미치는 요인
한국산업보건학회지
2018 .01
-
Relationship between fatigue severity scale and occupational injury in Korean workers
대한직업환경의학회지
2021 .05
-
근로자의 피로수준에 따른 직무 스트레스 및 삶의 질
한국직업건강간호학회지
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0