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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 45 - 55 (11page)
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초록· 키워드
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The Citrus grandis Osbeck is a special product in the Jeju island. The product has been as a remedy for liver damage and hang over. This study demonstrates how to investigate and compare the antioxidant, phenol content, tyrosinase and α-glucosidase inhibitory activity, antimicrobial, and alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activity with the C. grandis leaves extracted in different ethanol concentrations. From the yield, a 20% ethanol extract demonstrated the highest results among the other extracts. The distilled water extract showed the most abundant in a total phenol content and highest ABTS radical scavenging activity and reducing power assay. In the DPPH radical scavenging activity, α-glucosidase and tyrosinase inhibitory assay (used L-tyrosine as substrate), the 80% ethanol extract exhibited a higher value than other extracts. The 60% ethanol extract showed prominent activities in the tyrosinase inhibitory (used L-dopa as substrate), ADH and ALDH activity assay. In the minimum inhibitory concentration (MIC) assay, 60% and 80% ethanol extracts inhibited the bacterial growth almost similarly. Moreover, the gram-positive bacteria was more restrained than the gram-negative bacteria. The results revealed that the distilled water and 80% ethanol extract showed a relatively higher antioxidant activity compared to other extracts. The 60 ~ 80% ethanol extracts demonstrated potential tyrosinase, α -glucosidase inhibitory, antimicrobial, ADH and ALDH activities. Therefore, the C. grandis is suggested to be considered as a functional material for various proposes.
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참고문헌 (60)
참고문헌 신청
Al-Dabbagh B / 2018 / Antioxidant and anticancer activities of Trigonella foenum-graecum, Cassia acutifolia and Rhazya stricta / BMC Complem Altern M 18:240
Aumeeruddy-Elalfi Z / 2016 / Kinetic studies of tyrosinase inhibitory activity of 19 essential oils extracted from endemic and exotic medicinal plants / South Afr J Bot 103:89~94
Bensizerara D / 2013 / Antimicrobial activity of xerophytic plant (Cotula cinerea Delile) extracts against some pathogenic bacteria and fungi / Jordan J Biol Sci 6:266~271
Castro-Vazquez L / 2016 / Bioactive flavonoid, antioxidant behavior, and cytoprotective effects of dried grape fruits peels (Citrus paradisi Macf.) / Oxid med Cell Longev 2016
차재영 / 2009 / 알코올 대사 효소 alcohol dehydrogenase (ADH) 및 acetaldehyde dehydrogenase (ALDH) 활성에 미치는 아미노산의 영향 / 생명과학회지 19(9):1321~1327
Aumeeruddy-Elalfi Z / 2016 / Kinetic studies of tyrosinase inhibitory activity of 19 essential oils extracted from endemic and exotic medicinal plants / South Afr J Bot 103:89~94
Bensizerara D / 2013 / Antimicrobial activity of xerophytic plant (Cotula cinerea Delile) extracts against some pathogenic bacteria and fungi / Jordan J Biol Sci 6:266~271
Castro-Vazquez L / 2016 / Bioactive flavonoid, antioxidant behavior, and cytoprotective effects of dried grape fruits peels (Citrus paradisi Macf.) / Oxid med Cell Longev 2016
차재영 / 2009 / 알코올 대사 효소 alcohol dehydrogenase (ADH) 및 acetaldehyde dehydrogenase (ALDH) 활성에 미치는 아미노산의 영향 / 생명과학회지 19(9):1321~1327
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